CT Portography in Grading of Liver Cirrhosis

NCT ID: NCT03453580

Last Updated: 2018-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-09-25

Study Completion Date

2019-10-30

Brief Summary

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Esophageal variceal bleeding and hepatic encephalopathy are serious complications of hepatic cirrhosis, and they may lead to high mortality rate and severely threaten life quality of the patients

Detailed Description

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The occurrence and development of Esophageal variceal bleeding and hepatic encephalopathy are closely related with portal vein system diseases, such as collateral circulation of portal hypertension and portal vein thrombosis.

The prevention of Esophageal variceal bleeding and hepatic encephalopathy in hepatic cirrhosis has become a hot spot in clinical practice.

Three-dimensional reconstruction of images obtained by multi-slice spiral computed tomography portography (MSCTP) is clear, realistic, and accurate.

It can directly and quickly display all anatomical information of collateral portal vein system, and is recognized as a good method to display blood vessels

Conditions

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CT Portography Grading of Liver Cirrhosis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Interventions

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multislice computed tomography portography

imaging modality

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patients with cirrhosis and\\or portal hypertension diagnosed by; laboratory or radiological parameters.

Exclusion Criteria

* Patients with ligation, disconnection or shunting of esophageal varices. Patients with combined hepatic malignant tumor Patients with splenectomy. Patients with renal dysfunction or iodine allergy.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Doaa Hamza

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Mostafa Hashem Mahmoud, professor

Role: CONTACT

01000684012

Marwa Mohamed Samy Mohamed, lecturer

Role: CONTACT

01025260404

References

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Biecker E. Gastrointestinal Bleeding in Cirrhotic Patients with Portal Hypertension. ISRN Hepatol. 2013 Jul 22;2013:541836. doi: 10.1155/2013/541836. eCollection 2013.

Reference Type RESULT
PMID: 27335828 (View on PubMed)

Bajaj JS. Review article: potential mechanisms of action of rifaximin in the management of hepatic encephalopathy and other complications of cirrhosis. Aliment Pharmacol Ther. 2016 Jan;43 Suppl 1:11-26. doi: 10.1111/apt.13435.

Reference Type RESULT
PMID: 26618922 (View on PubMed)

Chu Q, Li Z, Zhang SM, Hu DY, Xiao M. Relationship between encephalopathy and portal vein-vena cava shunt: value of computed tomography during arterial portography. World J Gastroenterol. 2004 Jul 1;10(13):1939-42. doi: 10.3748/wjg.v10.i13.1939.

Reference Type RESULT
PMID: 15222041 (View on PubMed)

Other Identifiers

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MSCT GRADING

Identifier Type: -

Identifier Source: org_study_id

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