ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers

NCT ID: NCT04367857

Last Updated: 2025-04-04

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 1000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-04-18
• Study Completion Date: 2026-03-31

Brief Summary

The novel coronavirus (SARS-CoV-2) has spread all around the world and testing has posed a challenge globally. Health care providers are highly exposed and are an important group to test. On top of these concerns, health care workers are also stressed by the needs on responders in the COVID-19 crisis. The investigators will look at different ways to measure how common COVID-19 is among health care workers, how common is the presence of antibodies by serological tests (also known as serostatus). The investigators will describe health worker mental and emotional well-being and their coping strategies in their institutional settings. Lastly, the investigators will describe how knowing serostatus can affect individuals' mental and emotional well-being and how to cope in the midst of the COVID-19 response. This will help to how to better test and help healthcare workers in the COVID-19 pandemic and prepare for possible future outbreaks.

Detailed Description

The rapid spread of the novel coronavirus SARS-CoV-2 has resulted in pandemic levels and a global challenge in diagnosing infection. Diagnosing infection, defining recovery and immunity has been challenging. Health care providers in particular are very interested in knowing their status as they are highly exposed, and if infectious, can potentially transmit infection nosocomially (in the healthcare workplace setting) and to their household. In addition to understanding their exposure risk, infectious period, and immunity status, health care workers are reporting high levels of psychosocial distress including anxiety and burnout. The investigators aim to assess the baseline and cumulative seroprevalence of SARS-CoV-2 among health care workers using both quantitative and qualitative serological assays; describe psychosocial well-being and coping strategies among health workers in their institutional settings and describe how knowledge of one's serostatus affect psychosocial well-being, and coping strategies. Findings from this study will inform; 1) use of serological assays and testing algorithms, and 2) approaches to manage psychosocial stress for healthcare workers.

Conditions

Covid-19; Coronavirus Infection; Coronavirus

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Prior Positive polymerase chain reaction (PCR) and Recovered

Prior Positive PCR result, fully recovered, back at work and symptom free for greater than or equal than 14 days.

COVID-19 Serology

Intervention Type: OTHER

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

Intervention Type: BEHAVIORAL

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Never tested, history of COVID-19 Symptoms and Recovered

Never tested and history of COVID-19 symptoms and symptom-free for more than 14 days

COVID-19 Serology

Intervention Type: OTHER

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

Intervention Type: BEHAVIORAL

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Never tested and current COVID-19 Symptoms

Never tested and current COVID-19 Symptoms (e.g. referred by a provider or clinic)

COVID-19 Serology

Intervention Type: OTHER

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

Intervention Type: BEHAVIORAL

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Never tested and asymptomatic

Never tested and asymptomatic for COVID-19 symptoms, including asymptomatic health care worker

COVID-19 Serology

Intervention Type: OTHER

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

Intervention Type: BEHAVIORAL

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Interventions

COVID-19 Serology

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Intervention Type: OTHER

Health Care Worker Survey

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• 18 years of age or older
• NewYork-Presbyterian (NYP) healthcare personnel employee or affiliate
• Understands and reads English

Exclusion Criteria

• Younger than 18 years of age
• Mentally and/or physically unable to complete study requirements

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Columbia University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Magdalena Sobieszczyk, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Columbia University

Locations

NewYork-Presbyterian Hosptial/Columbia University Irving Medical Center

New York, New York, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Brett Gray

Role: CONTACT

bg2168@cumc.columbia.edu

212-305-1570

Facility Contacts

Brett Gray

Role: primary

Other Identifiers

AAAS9998

Identifier Type: -

Identifier Source: org_study_id