Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
NCT ID: NCT04366635
Last Updated: 2020-05-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
36 participants
INTERVENTIONAL
2020-04-27
2020-08-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Mineralised Plasmatic Matrix Group
Mineralized Plasmatic Matrix (MPM) is a product of mixing of two phases: the mineral phase and the plasma phase. After centrifugation, the white blood cells are recovered and mixed with the mineral phase of bone graft that can be autogenic, allogeneic bone, or a bone substitute like Xenogeneic Bone Synthetic. We will use Beta-tricalcium phosphate as a graft material. The result of this mixture is a homogeneous single component, which is compact and stable, containing the graft, the dense fibrin network, and the promoting healing. And then we are planning to place MPM material to extraction socket of impacted third molar tooth to improve periodontal healing at the distal aspect of second molar tooth. Additional after MPM places to extraction socket, Once the MPM has been placed, it will be covered with a Platelet Rich Fibrin (PRF) membrane and sutured as a primer.
Impacted third molar surgery
Under local anesthesia, flap will be raised and mesioangular or horizontal impacted third molar tooth will be removed with routine technique. And then extraction socket will be irrigated with salin and will be primarily closed.
Application of mineralised plasmatic matrix
After extraction of impacted third molar tooth, Mineralized Plasmatic Matrix will be placed to the socket as a graft material and will be covered with Platelet Rich Fibrin membrane. Then wound will be primarily closed.
Beta-tricalcium phosphate Group
Beta-tricalcium phosphate graft will place in the extraction socket and cover with a PRF membrane.
Impacted third molar surgery
Under local anesthesia, flap will be raised and mesioangular or horizontal impacted third molar tooth will be removed with routine technique. And then extraction socket will be irrigated with salin and will be primarily closed.
Application of β-tricalcium phosphate
After extraction of impacted third molar tooth, β-tricalcium phosphate will be placed to the socket as a graft material and will be covered with Platelet Rich Fibrin membrane. Then wound will be primarily closed.
Control Group
In the control group, after removal of impacted third molar tooth no material will be placed on the extraction socket. Only the extraction socket was primarily closed with non-resorbable sutures.
Impacted third molar surgery
Under local anesthesia, flap will be raised and mesioangular or horizontal impacted third molar tooth will be removed with routine technique. And then extraction socket will be irrigated with salin and will be primarily closed.
Interventions
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Impacted third molar surgery
Under local anesthesia, flap will be raised and mesioangular or horizontal impacted third molar tooth will be removed with routine technique. And then extraction socket will be irrigated with salin and will be primarily closed.
Application of mineralised plasmatic matrix
After extraction of impacted third molar tooth, Mineralized Plasmatic Matrix will be placed to the socket as a graft material and will be covered with Platelet Rich Fibrin membrane. Then wound will be primarily closed.
Application of β-tricalcium phosphate
After extraction of impacted third molar tooth, β-tricalcium phosphate will be placed to the socket as a graft material and will be covered with Platelet Rich Fibrin membrane. Then wound will be primarily closed.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Periodontally healthy patients.
* Patients with mesioangular or horizontal impacted teeth that will cause periodontal damage at the distal part of the second molar after surgery.
Exclusion Criteria
* Poor oral hygiene.
* Patients with a systemic disease affecting periodontal healing.
* Pregnancy or lactation period.
* Patients undergoing orthodontic treatment.
* Smokers.
* The cases where the buccal or lingual cortical bone didn't remain intact following the extraction were also excluded.
18 Years
40 Years
ALL
Yes
Sponsors
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Konya Necmettin Erbakan Üniversitesi
OTHER
Responsible Party
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Ali Kılınç
Research Assistant
Principal Investigators
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Kubilay Işık
Role: STUDY_CHAIR
Consultant
Ali Kılınç
Role: STUDY_DIRECTOR
Care Provider
Locations
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Necmettin Erbakan University, Faculty of dentistry
Konya, , Turkey (Türkiye)
Countries
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Central Contacts
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Kubilay Işık
Role: CONTACT
Facility Contacts
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Kubilay Işık
Role: primary
Other Identifiers
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KonyaNEU1
Identifier Type: -
Identifier Source: org_study_id
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