Collection of Biological Samples With Clinical Characterization of Covid-19 Patients

NCT ID: NCT04363385

Last Updated: 2024-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

500 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-05-31

Study Completion Date

2023-05-31

Brief Summary

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Biological collection (blood sample) associated with clinical data from Covid-19 patients

Detailed Description

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SARS-Cov2 is an emerging respiratory virus in the coronavirus family, responsible of the pandemic since November 2019. France, which has more than 17,000 deaths from the virus, is one of the main outbreaks. As of 16 April 2020, more than 76,000 individuals in France have been hospitalized, corresponding to 69% of confirmed cases (https://www.santepubliquefrance.fr).

Most affected patients have more or less marked clinical signs associating fever, cough, dyspnea, myalgia, anosmia, ageusia, digestive disorders. In some cases, the progression is worse with lung disease of varying severity. Indications for hospitalization are essentially the severe forms of Covid-19 disease, characterized by hypoxemic lung disease.

Risk factors for developing severe Covid-19 disease have been identified already: age, co-morbidity such as diabetes, obesity-overweight or cardiovascular diseases. It is assumed that other host-related factors, including genetics, may contribute to the existence of this phenotypic heterogeneity. At present, these factors are not known.

The objective of this research is to constitute a DNA collection from patients with Covid-19, in order to be able to search for genetic factors modulating the clinical phenotype.

Conditions

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Covid-19

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Collection of blood samples in a cohort of Covid-19 patients
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Collection of blood sample

Group Type OTHER

Biological test

Intervention Type BIOLOGICAL

Blood sample

Interventions

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Biological test

Blood sample

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of COVID-19 confirmed on RT-PCR test or chest scanner
* Any age
* Membership in the general social security system
* Inform consent signed by the patient or by legal representatives for minors

Exclusion Criteria

* Refusal of the patient or one of the legal representatives
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Intercommunal Creteil

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre hospitalier intercommunal de Créteil

Créteil, , France

Site Status

Countries

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France

Other Identifiers

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COVIGENET

Identifier Type: -

Identifier Source: org_study_id

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