Propensity Score Matched Comparison of HMP vs. SCS in Kidney Transplantation

NCT ID: NCT04359173

Last Updated: 2020-04-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

347 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-08-01

Study Completion Date

2020-03-30

Brief Summary

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Hypothermic machine perfusion (HMP) is considered superior to static cold storage (SCS) in kidney transplantation, but the true benefit in the real-world experience remains incompletely understood.

The aim of our study is to investigate the real-world impact of HMP on kidney graft function after deceased donor kidney transplant in an HMP cohort propensity score matched with SCS.

Propensity score matching will be based on CIT, ECD, gender mismatch, CMV mismatch, re-TX and ET-senior program with a caliper of 0.05

Detailed Description

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Conditions

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Delayed Graft Function

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Hypothermic machine perfusion (HMP)

patients who underwent kidney transplantation following HMP

No interventions assigned to this group

Static cold storage (SCS)

patients who underwent kidney transplantation following SCS

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* single kidney transplantation from a deceased donor at Medical University of Innsbruck between 08/2015 and 12/2019

Exclusion Criteria

* combined kidney transplantation with an other organ
* living donor kidney transplantation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University Innsbruck

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stefan Schneeberger, Prof.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Innsbruck

Locations

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Medical University of Innsbruck

Innsbruck, Tyrol, Austria

Site Status

Countries

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Austria

Other Identifiers

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HMP_SCS

Identifier Type: -

Identifier Source: org_study_id

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