A Short-term Mixed Exercise for Sarcopenic Hospitalized Aged 80+ Years

NCT ID: NCT04355299

Last Updated: 2020-04-22

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 121 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-10-01
• Study Completion Date: 2020-01-01

Brief Summary

Most previous clinical trials that addressed exercise for sarcopenic elderly subjects focused on community-dwelling older adults who were relatively healthy. There is a notable paucity of high-quality research investigating the effects and feasibility of exercise for hospitalized or institutionalized older people, who are generally frailer and more severe in functional impairment than those living in the community. Moreover, most reported exercise programs were of long-term duration, which typically lasted 3 to 6 months with two sessions per week. It remains unclear whether short-term exercise would be effective for treating sarcopenia. Therefore, the investigators aimed to assess the effectiveness of short-term exercise for treating sarcopenia in hospitalized older patients aged 80 years and over.

Conditions

Sarcopenia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Intervention group

a mixed exercise program including aerobic, balance, and resistance exercises that were personally tailored.

Group Type: EXPERIMENTAL

balance training

Intervention Type: BEHAVIORAL

The training to improve balance is to work on the core muscle groups that help to maintain your posture.,and increase muscular strength.

resistance training

Intervention Type: BEHAVIORAL

Resistance training is a form of exercise that improves muscular strength and endurance. During a resistance training workout, you move your limbs against resistance provided by your body weight, gravity, bands, weighted bars or dumbbells.

aerobic exercise

Intervention Type: BEHAVIORAL

Aerobic exercise is any activity that gets your blood pumping and large muscle groups working. It's also known as cardiovascular activity.

control group

usual care

Group Type: OTHER

usual care

Intervention Type: BEHAVIORAL

received usual care

Interventions

balance training

The training to improve balance is to work on the core muscle groups that help to maintain your posture.,and increase muscular strength.

Intervention Type: BEHAVIORAL

resistance training

Resistance training is a form of exercise that improves muscular strength and endurance. During a resistance training workout, you move your limbs against resistance provided by your body weight, gravity, bands, weighted bars or dumbbells.

Intervention Type: BEHAVIORAL

aerobic exercise

Aerobic exercise is any activity that gets your blood pumping and large muscle groups working. It's also known as cardiovascular activity.

Intervention Type: BEHAVIORAL

usual care

received usual care

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. aged ≥80 years;

2. being able to ambulate (assistance was acceptable);

3. being able to communicate and collaborate with the physiotherapist;

4. with sarcopenia defined by the AWGS criteria ;

Exclusion Criteria

1. terminal illness;

2. uncontrolled heart failure;

3. myocardial infarction within the past three months;

4. uncontrolled respiratory failure;

5. bone fractures within the past three months;

6. acute pulmonary embolism;

7. major surgery within the past three months;

8. uncontrolled arrhythmia;

9. refusal to participate in this study.

• Minimum Eligible Age: 80 Years
• Maximum Eligible Age: 102 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Yuxiang Liang

OTHER

Sponsor Role: lead

Responsible Party

Yuxiang Liang

Physiotherapist

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Jiaojiao Jiang

Role: PRINCIPAL_INVESTIGATOR

West China Hospital

Ming Yang

Role: STUDY_DIRECTOR

West China Hospital

Other Identifiers

2019#611#

Identifier Type: -

Identifier Source: org_study_id