Clinical Trial Protocol for Safety and Efficacy of Soft Contact Lens

NCT ID: NCT04299243

Last Updated: 2020-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

148 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-11-25

Study Completion Date

2019-06-01

Brief Summary

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This project is a multi-center, randomized, parallel-controlled, non-inferior clinical trial of soft contact lenses.

Detailed Description

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The test product is the Soft Contact Lens (model: Spherical Lens), and the control product is a commercially available soft contact lens (model: SiHy Daily). The number of enrolled subjects is 148, and clinical observation is performed for 3 months.

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Spherical Lens

Randomized to Spherical Lens worn in a daily disposable mode

Group Type EXPERIMENTAL

Contact Lenses

Intervention Type DEVICE

Contact lenses for vision correction

SiHy Daily

Randomized to SiHy Daily worn in a daily disposable mode

Group Type ACTIVE_COMPARATOR

Contact Lenses

Intervention Type DEVICE

Contact lenses for vision correction

Interventions

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Contact Lenses

Contact lenses for vision correction

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female with age of 18 to 45
* Spherical power: -0.25 to -10.00D
* Cylinder power ≤0.75D and Sph.P:Cyl.P≥3:1, or 1.00D≤ cylinder power ≤1.50D and Sph.P:Cyl.P ≥4:1;
* Both eyes are ametropia, and there is no case where the investigator believes that the soft contact lens cannot be worn;

: The case of wearing a soft contact lens as referred to in this trial is: i) No eyelid abnormalities or infections; ii) No clinically significant slit lamp findings iii) No other active eye diseases.
* BCVA of the left and right eye subjective refraction is greater than or equal to 5.0.

Exclusion Criteria

* Need to use therapeutic ophthalmic drugs, including antibiotics, hormones and compound ophthalmic drugs containing hormones
* Dry eye syndrome
* Any systemic disease contraindications to contact lenses or disease medications can affect the wearing of contact lenses
* Wearing a hard contact lens in the past 6 weeks
* Tear film break-up time is less than or equal to 5s
* Allergic to contact lenses and/or contact lenses
* Keratoconus or other irregular corneal patients
* Soft hydrophilic contact lens wearers are affected by long-term special conditions such as dryness, severe dust or volatile chemicals
* Pregnant, lactating or plan to be pregnant
* Only one eye meets the requirements for enrollment
* Participating in other clinical trials or less than ten days after the end of a soft contact lens clinical trial
* Less than three months after the end of a drug clinical trial
* Determined by the investigator that could not be enrolled
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Menicon Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Li Lihua, MD

Role: PRINCIPAL_INVESTIGATOR

Tianjin Eye Hospital

Locations

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Tianjin Eye Hospital

Tianjin, , China

Site Status

Countries

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China

Other Identifiers

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SLP-01

Identifier Type: -

Identifier Source: org_study_id

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