Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
120 participants
OBSERVATIONAL
2019-02-01
2021-01-31
Brief Summary
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Detailed Description
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NRD will be calculated as root mean square of normal tidal breathing as a proportion of maximal inspiratory effort (maximum inspiration from functional reserve capacity, taken as a sniff manoeuvre). Measurements will be performed in a ward based setting at the patient's bedside.
At the end of the inpatient stay for diagnosis, some patients are commenced on treatment and followed up in clinic. It would be the intention of the investigators to reassess these patients at clinic to test NRD and compare how this changes over time compared to other clinical parameters.
In addition, we will collect further readings of NRD in these patients when they attend for their standard follow up appointment. For the majority of patients, this will be after 3-4 months. For a subset of patients with chronic thromboembolic pulmonary hypertension, this may be up to one year after initial readings because these patients may be suitable for surgical intervention, which is not done locally and usually takes place 6-12 months after diagnosis at SPVU.
As such, the investigators intend that a patient will take part in the study for 52 weeks maximum, with most patients taking part for 16 weeks, and the study will not require them to have any additional attendances at hospital outwith their standard hospital admission for diagnosis and clinic follow up.
Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Interventions
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Parasternal electromyogram measurement
Three electrodes are applied to the chest (two to parasternal muscles, one reference electrode to clavicle). Measurements of EMG signals are recorded on appropriate software.
Eligibility Criteria
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Inclusion Criteria
* Being investigated for pulmonary hypertension
Exclusion Criteria
* Patient has a diagnosed neuromuscular disorder
18 Years
90 Years
ALL
No
Sponsors
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Golden Jubilee National Hospital
OTHER_GOV
Responsible Party
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Principal Investigators
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Martin Johnson
Role: PRINCIPAL_INVESTIGATOR
NHS Greater Glasgow and Clyde
Locations
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Golden Jubilee National Hospital
Glasgow, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Provided Documents
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Document Type: Study Protocol
Document Type: Informed Consent Form
Other Identifiers
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18/CARD/32
Identifier Type: -
Identifier Source: org_study_id
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