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Inspiratory Muscle Training in Pulmonary Arterial Hypertension

NCT ID: NCT04197388

Last Updated: 2019-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-26

Study Completion Date

2021-04-01

Brief Summary

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Pulmonary arterial hypertension is a rare condition characterised by high blood pressure in the lungs and results in breathlessness and reduced exercise capacity for patients. Previous research has shown weakness in respiratory muscles in these patients that may contribute towards their symptoms. Despite advances in medical therapy, the condition still results in a significant symptom burden.

Inspiratory muscle training is a non-invasive intervention involving a device that provides resistance to the muscles of inspiration and increases their strength.

This study will investigate the benefit of inspiratory muscle training in patients with pulmonary arterial hypertension who are stable on medical therapy for three months. This will be performed as an outpatient and they will then be reviewed following this with assessment of exercise capacity, breathing capacity (spirometry), quality of life, and assessment of neural respiratory drive (the signals from the brain to the muscles controlling breathing).

The study will be based at the Golden Jubilee National Hospital and patients will be recruited from outpatients who are already under the care of the Scottish Pulmonary Vascular Unit.

Detailed Description

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Conditions

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Pulmonary Hypertension

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Inspiratory muscle training device

Inspiratory muscle training, 6 cycles of 30 breaths for 12 weeks.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* diagnosed by pulmonary hypertension specialist with precapillary pulmonary hypertension
* able to give consent
* stable on medical therapy for at least 3 months

Exclusion Criteria

* significant contribution to pulmonary hypertension from lung disease
* pregnant
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Golden Jubilee National Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Golden Jubilee National Hospital

Glasgow, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Paul McCaughey

Role: CONTACT

Phone: 07907029041

Email: [email protected]

Facility Contacts

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Paul McCaughey

Role: primary

Other Identifiers

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18/CARD/31

Identifier Type: -

Identifier Source: org_study_id