Hypoperfusion-hypodensity Mismatch for the Identification of Patients With Stroke Within 4.5 Hours
NCT ID: NCT04277728
Last Updated: 2020-02-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
689 participants
OBSERVATIONAL
2018-01-01
2019-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Interventions
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hypoperfusion-hypodensity mismatch
hypoperfusion-hypodensity mismatch on computed tomography
Eligibility Criteria
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Inclusion Criteria
* evidence of acute intracranial vessel occlusion (any supratentorial proximal or peripheral artery of the anterior cerebral artery, middle cerebral artery or posterior cerebral artery territory) by CT hyper dense thrombus and/or CTangiography vessel occlusion and/or by ischemic perfusion deficit
* evidence for acute ischemic perfusion deficit, i.e. acute symptoms attributable to ischemic CT perfusion lesion
* complete native CT and CTperfusion performed on admission
* sufficient CT and CTperfusion quality for judgement of acute ischemic hypodensity
* known time of symptom onset.
Exclusion Criteria
18 Years
ALL
No
Sponsors
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University Hospital Muenster
OTHER
Responsible Party
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Principal Investigators
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Jens Minnerup, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital Muenster
Locations
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University Hospital Münster
Münster, , Germany
Countries
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References
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Sporns PB, Kemmling A, Meyer L, Krogias C, Puetz V, Thierfelder KM, Duering M, Lukas C, Kaiser D, Langner S, Brehm A, Rotkopf LT, Kunz WG, Beuker C, Heindel W, Fiehler J, Schramm P, Wiendl H, Minnerup H, Psychogios MN, Minnerup J. Computed tomography hypoperfusion-hypodensity mismatch vs. automated perfusion mismatch to identify stroke patients eligible for thrombolysis. Front Neurol. 2023 Dec 29;14:1320620. doi: 10.3389/fneur.2023.1320620. eCollection 2023.
Sporns PB, Kemmling A, Minnerup H, Meyer L, Krogias C, Puetz V, Thierfelder K, Duering M, Kaiser D, Langner S, Massoth C, Brehm A, Rotkopf L, Kunz WG, Karch A, Fiehler J, Heindel W, Schramm P, Royl G, Wiendl H, Psychogios M, Minnerup J. CT Hypoperfusion-Hypodensity Mismatch to Identify Patients With Acute Ischemic Stroke Within 4.5 Hours of Symptom Onset. Neurology. 2021 Nov 23;97(21):e2088-e2095. doi: 10.1212/WNL.0000000000012891. Epub 2021 Oct 14.
Other Identifiers
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100001
Identifier Type: -
Identifier Source: org_study_id
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