Evaluation of Adipose Derived Stem Cells Exo.in Treatment of Periodontitis

NCT ID: NCT04270006

Last Updated: 2020-02-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-12

Study Completion Date

2021-10-31

Brief Summary

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The adipose stem cells exosomes will be extracted from adipose stem cells isolated autogenously from the patient to be injected locally into the periodontal pockets in order to evaluate their regenerative effect.

Detailed Description

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Conditions

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Periodontitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Exosomes

Group Type EXPERIMENTAL

adipose derived stem cells exosomes

Intervention Type BIOLOGICAL

they are small extracellular vesicles

Interventions

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adipose derived stem cells exosomes

they are small extracellular vesicles

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Advanced periodontitis (Stage III or IV)
* Healthy patients.

Exclusion Criteria

* Smokers, Diabetic, Pregnant ladies, Under corticosteroids or contraceptive treatment,poor oral hygiene.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beni-Suef University

OTHER

Sponsor Role lead

Responsible Party

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Ebtehal Mohammed

Lecturer of oral medicine, periodontotlogy and oral diagnosis

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ebtehal Mohammed, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Lecturer of Oral Medicine , Oral diagnosis and Periodontology , Faculty of Dentistry, Beni- Suef University.

Nesrine Mohammed Khairy, Associated Professor

Role: STUDY_DIRECTOR

Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University

Noha Saleh Mohammed, Associated

Role: STUDY_DIRECTOR

Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University.

Dina Sabry, Professor

Role: STUDY_DIRECTOR

Biochemistry, Faculty of Medicine, Cairo University

Locations

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Beni-Suef University

Banī Suwayf, , Egypt

Site Status RECRUITING

Cairo University

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ebtehal Mohammed, Ph.D

Role: CONTACT

01224336896

Noha Saleh, Ph.D

Role: CONTACT

Facility Contacts

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Ebtehal Mohammed, lecturer

Role: primary

01224336896

Ebtehal Mohammed

Role: primary

01224336896

Other Identifiers

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FDBSUREC/21012020/ME

Identifier Type: -

Identifier Source: org_study_id

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