Music Therapy and Bio-psychological Effect Among Chronic Psychiatric Inpatients of a Community Teaching Hospital

NCT ID: NCT04254965

Last Updated: 2020-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-29

Study Completion Date

2020-12-31

Brief Summary

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Negative symptoms are an important factor in preventing patients from returning to the community, we aim to assess the effect of music therapy on negative symptoms through this study. Participants of integrated music therapy will receive instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. Other participants will receive passive music listening or regular occupational therapy during the experimental period. Psychiatric symptoms, quality of life, social and interactive skills, and the differences in the physiological signals produced by skin, muscles, and heart will be measured before, after, and two months after the music therapy.

Detailed Description

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Music therapy is gradually being used in the field of psychiatry, such as depression, anxiety, and development disorders in children. However, music therapy still lacks systematic research on chronic mental illness. Since negative symptoms are an important factor in preventing patients from returning to the community, we aim to assess the effect of music therapy on negative symptoms through this study. Additionally, Taiwan as many Asian countries have not yet established a certification system for music therapy. This study cooperates with licensed therapists abroad in the hope of promoting the systematic development of local music therapy in the future.

Participants of integrated music therapy (Group 1, integration of active and passive music therapy) includes instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. The four stages of activities are warm-up, main activities, secondary activities, and the ending section. The participants of the music listening group (Group 2, background music listening), music selection based on the musical preference and background of subjects, for relax or boost the spirit of the subjects. Participants in the control group (Group 3) receive their regular occupational therapy during the experimental period. We plan to recruit 100 people in the wards: 40/20/40 (Group 1/2/3) under random assignment.

To evaluate the effects of three groups, we measure their psychiatric symptoms, quality of life, social and interactive skills, and the differences in the physiological signals produced by skin, muscles, and heart assisted by a medical engineering scholar before, after, and two months after the music therapy.

Conditions

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Chronic Psychosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Group 1

Participants of integrated music therapy (integration of active and passive music therapy) includes instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process. The four stages of activities are warm-up, main activities, secondary activities, and the ending section.

Group Type EXPERIMENTAL

Music therapy

Intervention Type OTHER

Treatment including instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process.

Biosignal analysis

Intervention Type DEVICE

Measurement of facial expression emotion recognition, electrodermal activity, heart rate variability, sleep pattern, blood pressure, and electromyogram.

Group 2

Participants of the music listening group will receive background music listening, music selection based on the musical preference and background of subjects, for relax or boost the spirit of the subjects.

Group Type ACTIVE_COMPARATOR

Music therapy

Intervention Type OTHER

Treatment including instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process.

Biosignal analysis

Intervention Type DEVICE

Measurement of facial expression emotion recognition, electrodermal activity, heart rate variability, sleep pattern, blood pressure, and electromyogram.

Group 3

Participants in the control group receive their regular occupational therapy during the experimental period.

Group Type SHAM_COMPARATOR

Biosignal analysis

Intervention Type DEVICE

Measurement of facial expression emotion recognition, electrodermal activity, heart rate variability, sleep pattern, blood pressure, and electromyogram.

Interventions

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Music therapy

Treatment including instrument playing, singing, lyrics modification/music organized play, listening to music and discussing each treatment process.

Intervention Type OTHER

Biosignal analysis

Measurement of facial expression emotion recognition, electrodermal activity, heart rate variability, sleep pattern, blood pressure, and electromyogram.

Intervention Type DEVICE

Other Intervention Names

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iMotions GSR-Shimmer Module Dailycare Fitbit DELYSYS TrignoTM Flex

Eligibility Criteria

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Inclusion Criteria

* Chronic patient in rehabilitation ward without compulsory hospitalization.
* Patients with mental, behavioral and neurodevelopmental disorders, including schizophrenia, schizotypal personality disorders, delusional disorders, affective disorders, and organic mental disorders.

Exclusion Criteria

* Patients with hearing impairments.
* Patients with no capacity to make juridical acts.
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Tsing Hua University

OTHER

Sponsor Role collaborator

National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Cheng-Che Chen, MDMPH

Role: PRINCIPAL_INVESTIGATOR

National Taiwan University Hospital Chu-Tung Branch

Locations

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National Taiwan University Hospital

Hsinchu, Hsinchu County, Taiwan

Site Status

Countries

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Taiwan

Central Contacts

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Haifan Hsu

Role: CONTACT

0980230620

Facility Contacts

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Cheng-Che Chen, MDMPH

Role: primary

03-5943248

References

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Gold C, Rolvsjord R, Aaro LE, Aarre T, Tjemsland L, Stige B. Resource-oriented music therapy for psychiatric patients with low therapy motivation: protocol for a randomised controlled trial [NCT00137189]. BMC Psychiatry. 2005 Oct 31;5:39. doi: 10.1186/1471-244X-5-39.

Reference Type BACKGROUND
PMID: 16259626 (View on PubMed)

Buccheri R, Trygstad L, Dowling G, Hopkins R, White K, Griffin JJ, Henderson S, Suciu L, Hippe S, Kaas MJ, Covert C, Hebert P. Long-term effects of teaching behavioral strategies for managing persistent auditory hallucinations in schizophrenia. J Psychosoc Nurs Ment Health Serv. 2004 Jan;42(1):18-27. doi: 10.3928/02793695-20040101-09.

Reference Type BACKGROUND
PMID: 14768276 (View on PubMed)

Acil AA, Dogan S, Dogan O. The effects of physical exercises to mental state and quality of life in patients with schizophrenia. J Psychiatr Ment Health Nurs. 2008 Dec;15(10):808-15. doi: 10.1111/j.1365-2850.2008.01317.x.

Reference Type BACKGROUND
PMID: 19012672 (View on PubMed)

Cook JD. Music as an intervention in the oncology setting. Cancer Nurs. 1986 Feb;9(1):23-8. No abstract available.

Reference Type BACKGROUND
PMID: 3518914 (View on PubMed)

Wiersma D, Jenner JA, Nienhuis FJ, van de Willige G. Hallucination focused integrative treatment improves quality of life in schizophrenia patients. Acta Psychiatr Scand. 2004 Mar;109(3):194-201. doi: 10.1046/j.0001-690x.2003.00237.x.

Reference Type BACKGROUND
PMID: 14984391 (View on PubMed)

Morgan KA, Harris AW, Luscombe G, Tran Y, Herkes G, Bartrop RW. The effect of music on brain wave functioning during an acute psychotic episode: a pilot study. Psychiatry Res. 2010 Jul 30;178(2):446-8. doi: 10.1016/j.psychres.2010.04.020. Epub 2010 May 14.

Reference Type BACKGROUND
PMID: 20471105 (View on PubMed)

Silverman MJ. Psychiatric patients' perception of music therapy and other psychoeducational programming. J Music Ther. 2006 Summer;43(2):111-22. doi: 10.1093/jmt/43.2.111.

Reference Type BACKGROUND
PMID: 16897904 (View on PubMed)

Peng SM, Koo M, Kuo JC. Effect of group music activity as an adjunctive therapy on psychotic symptoms in patients with acute schizophrenia. Arch Psychiatr Nurs. 2010 Dec;24(6):429-34. doi: 10.1016/j.apnu.2010.04.001. Epub 2010 May 21.

Reference Type BACKGROUND
PMID: 21111297 (View on PubMed)

Ulrich G, Houtmans T, Gold C. The additional therapeutic effect of group music therapy for schizophrenic patients: a randomized study. Acta Psychiatr Scand. 2007 Nov;116(5):362-70. doi: 10.1111/j.1600-0447.2007.01073.x.

Reference Type BACKGROUND
PMID: 17919155 (View on PubMed)

Hayashi N, Tanabe Y, Nakagawa S, Noguchi M, Iwata C, Koubuchi Y, Watanabe M, Okui M, Takagi K, Sugita K, Horiuchi K, Sasaki A, Koike I. Effects of group musical therapy on inpatients with chronic psychoses: a controlled study. Psychiatry Clin Neurosci. 2002 Apr;56(2):187-93. doi: 10.1046/j.1440-1819.2002.00953.x.

Reference Type BACKGROUND
PMID: 11952923 (View on PubMed)

Chou MH, Lin MF. Exploring the listening experiences during guided imagery and music therapy of outpatients with depression. J Nurs Res. 2006 Jun;14(2):93-102. doi: 10.1097/01.jnr.0000387567.41941.14.

Reference Type BACKGROUND
PMID: 16741859 (View on PubMed)

Talwar N, Crawford MJ, Maratos A, Nur U, McDermott O, Procter S. Music therapy for in-patients with schizophrenia: exploratory randomised controlled trial. Br J Psychiatry. 2006 Nov;189:405-9. doi: 10.1192/bjp.bp.105.015073.

Reference Type BACKGROUND
PMID: 17077429 (View on PubMed)

Hars M, Herrmann FR, Gold G, Rizzoli R, Trombetti A. Effect of music-based multitask training on cognition and mood in older adults. Age Ageing. 2014 Mar;43(2):196-200. doi: 10.1093/ageing/aft163. Epub 2013 Nov 7.

Reference Type BACKGROUND
PMID: 24212920 (View on PubMed)

Tseng PT, Chen YW, Lin PY, Tu KY, Wang HY, Cheng YS, Chang YC, Chang CH, Chung W, Wu CK. Significant treatment effect of adjunct music therapy to standard treatment on the positive, negative, and mood symptoms of schizophrenic patients: a meta-analysis. BMC Psychiatry. 2016 Jan 26;16:16. doi: 10.1186/s12888-016-0718-8.

Reference Type BACKGROUND
PMID: 26812906 (View on PubMed)

Other Identifiers

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201908035RINC

Identifier Type: -

Identifier Source: org_study_id

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