Effect of Transcutaneous Electrical Nerve Stimulation in Diabetic Neuropathy

NCT ID: NCT04253860

Last Updated: 2021-08-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-01

Study Completion Date

2021-07-30

Brief Summary

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Double-blind, randomized, placebo-controlled, clinical trial. Patients with diabetic neuropathy will be randomly assigned to treatment with either TENS or TENS sham three times a week during 90 days. Clinical determinations are: pain, levesls of TNF-alpha, IL-6 and RPC-us

Detailed Description

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Conditions

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Diabetic Neuropathy Peripheral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized, double-blind, clinical trial
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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TENS

Transcutaneous electrical neurostimulation will be applied for 30 minutes three times a week during 90 days

Group Type EXPERIMENTAL

Transcutaneous electrical neurostimulation

Intervention Type DEVICE

Sessions of 30 minutes of TENS will be applied three times a week during 90 days

Sham

A sham comparator will be applied for 30 minutes three times a week during 90 days. The device does not emit electrical impulses

Group Type SHAM_COMPARATOR

Transcutaneous electrical neurostimulation

Intervention Type DEVICE

Sessions of 30 minutes of TENS will be applied three times a week during 90 days

Interventions

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Transcutaneous electrical neurostimulation

Sessions of 30 minutes of TENS will be applied three times a week during 90 days

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diagnostic of type 2 diabetes \> 10 years
* Diagnostic of peripheral diabetic neuropathy less than 5 years
* HbA1C \> 6.5 and \< 9%
* Plasmatic glucose \>140 mg/dL and lees than 350 mg/dL
* Informed consent signed

Exclusion Criteria

* Use of implanted pacemaker or heart defibrillator
* Implanted brain stimulator
* History of alcohol abuse
* Use of NSAID, stereoids
* Subjects with wounds, ulcers in legs
* Subjects with hepatic, renal o neurologic diseases
Minimum Eligible Age

45 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Guadalajara

OTHER

Sponsor Role collaborator

Diabetes sin Complicaciones S.A de C.V, Mexico

UNKNOWN

Sponsor Role collaborator

Centro Universitario de Tonalá

OTHER

Sponsor Role lead

Responsible Party

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Arieh Roldán Mercado Sesma

Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Arieh R Mercado Sesma, PhD

Role: PRINCIPAL_INVESTIGATOR

Salud Enfermedad como proceso individual, CUTonalá, Universidad de Guadalajara

Locations

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University of Guadalajara

Guadalajara, Jalisco, Mexico

Site Status

Countries

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Mexico

Other Identifiers

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TENS-ND-2018

Identifier Type: -

Identifier Source: org_study_id

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