Transcutaneous Pulsed Radiofrequency in Diabetic Polyneuropathy

NCT ID: NCT05480527

Last Updated: 2023-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-01

Study Completion Date

2023-12-01

Brief Summary

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Investigators want to investigate the efficacy of transcutaneous pulsed radiofrequency therapy in the treatment of diabetic peripheral neuropathy symptoms. For this purpose, investigators aimed to compare the results of two groups treated with sham electrode and active electrode.

Detailed Description

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Peripheral neuropathic pain is common in diabetes mellitus. Distal symmetrical polyneuropathy is the most common form. These patients have complaints such as burning, freezing, tingling and pain in their hands and feet. Peripheral nerve blocks or sympathetic blocks are applied to patients who cannot be treated with medical agents.

Transcutaneous pulsed radiofrequency is a method used in the treatment of pain. The advantages of transcutaneous pulsed radiofrequency method are that it is not invasive, does not cause side effects, and does not interact with drugs. We want to investigate the efficacy of diabetic peripheral neuropathic pain treatment with this method.

Sixty diabetic polyneuropathy patients will be included in the study. Transcutaneous pulsed radiofrequency therapy with active electrode will be applied to half of the patients. Sham electrode will be used for the other half. Patients will not know which group they belong to. Two treatments will be applied with 7 days intervals. The duration of treatment will be 8 minutes.Each patient will receive a Leeds Assessment of Neuropathic Symptoms and Signs questionnaire (LANSS). Before the treatment, in the first month and third month after the treatment, the patients will be filled with a visual analog scale. The results between both groups will be statistically compared.

Conditions

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Neuropathy;Peripheral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Patients with bilateral neuropathic pain which treating active electrode

30 patients which treating with transcutaneous pulsed radiofrequency. All patients have diabetic polyneuropathy and confirmed with electroneuromyography.

Group Type ACTIVE_COMPARATOR

Transcutaneous pulsed radiofrequency current

Intervention Type DEVICE

Active treating group: 80 volts, 2Hz, 20 ms pulsed radiofrequency current will be applied to the tibial nerve trace in the ankle with electrodes. Sham group: Elelctrodes will be attached but radiofrequency current will not be applied.

Patients with bilateral neuropathic pain which applied sham electrode

Sham electrodes will be applied to 30 patients. All patients have diabetic polyneuropathy and confirmed with electroneuromyography.

Group Type SHAM_COMPARATOR

Transcutaneous pulsed radiofrequency current

Intervention Type DEVICE

Active treating group: 80 volts, 2Hz, 20 ms pulsed radiofrequency current will be applied to the tibial nerve trace in the ankle with electrodes. Sham group: Elelctrodes will be attached but radiofrequency current will not be applied.

Interventions

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Transcutaneous pulsed radiofrequency current

Active treating group: 80 volts, 2Hz, 20 ms pulsed radiofrequency current will be applied to the tibial nerve trace in the ankle with electrodes. Sham group: Elelctrodes will be attached but radiofrequency current will not be applied.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of Diabetes Mellitus
* Peripheric neuropathy with proved electroneuromyography

Exclusion Criteria

* Additional endocrinological disease,
* Pregnancy, malignancy, motor deficit in lower extremities
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Diskapi Teaching and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Damla Yürük

Director, medical doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mehlika Panpallı Ateş

Role: STUDY_CHAIR

Diskapi Yildirim Beyazit Education and Research Hospital

Damla Yürük

Role: STUDY_CHAIR

Diskapi Yildirim Beyazit Education and Research Hospital

Ömer Taylan Akkaya

Role: STUDY_DIRECTOR

Diskapi Yildirim Beyazit Education and Research Hospital

Locations

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Dişkapi Reserch and Education Hospital

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Gevher Rabia Genc Perdecioglu

Role: CONTACT

05332009184

Mehlika Panpallı Ateş

Role: CONTACT

5337122286

Facility Contacts

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damla S YURUK

Role: primary

5319932378 ext. 5319932378

Ömer Taylan S Akkaya

Role: backup

5067152323 ext. 5319932378

Other Identifiers

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Diabetic PNP

Identifier Type: -

Identifier Source: org_study_id

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