Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite

NCT ID: NCT04248803

Last Updated: 2025-10-17

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

570 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-06

Study Completion Date

2025-02-20

Brief Summary

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To evaluate the effect of Gluma desensitizer in controlling immediate post-treatment sensitivity in posterior occlusal composite restorations.

Detailed Description

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The primary objective of this study is to observe the effect of gluma desensitizer application in controlling the post-treatment sensitivity in posterior occlusal composite restoration in molar teeth using 2 adhesive bonding strategies.

The secondary objective is to evaluate the difference in the post-treatment sensitivity on application of Gluma desensitizer either prior to or after acid etching.

The different adhesive gluma desensitizer application groups are randomly divided into 6 groups,

1. Total etch control group (No gluma desensitizer application)
2. Total etch group Gluma (Kulzer GmbH, Germany) desensitizer application prior to acid etching
3. Total etch group Gluma (Kulzer GmbH, Germany) desensitizer application after acid etching
4. Self etch control group (No gluma desensitizer application)
5. Self etch group Gluma (Kulzer GmbH, Germany) desensitizer application prior to acid etching
6. Self etch group Gluma (Kulzer GmbH, Germany) desensitizer application after acid etching

Conditions

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Sensitivity, Tooth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Total etch control group

No gluma desensitizer application

Group Type NO_INTERVENTION

No interventions assigned to this group

TE - GLUMA application prior to acid etching

TE- Total Etch GLUMA - Desensitizing agent

Group Type EXPERIMENTAL

GLUMA (Kulzer GmbH, Germany) desensitizing agent

Intervention Type OTHER

GLUMA desensitizer is used to reduce tooth sensitivity

TE - GLUMA application after acid etching

TE- Total Etch GLUMA - Desensitizing agent

Group Type EXPERIMENTAL

GLUMA (Kulzer GmbH, Germany) desensitizing agent

Intervention Type OTHER

GLUMA desensitizer is used to reduce tooth sensitivity

Self etch control group

No gluma desensitizer application

Group Type NO_INTERVENTION

No interventions assigned to this group

SE - GLUMA application prior to acid etching

SE - Self Etch GLUMA - Desensitizing agent

Group Type EXPERIMENTAL

GLUMA (Kulzer GmbH, Germany) desensitizing agent

Intervention Type OTHER

GLUMA desensitizer is used to reduce tooth sensitivity

SE - GLUMA application after acid etching

SE - Self Etch GLUMA - Desensitizing agent

Group Type EXPERIMENTAL

GLUMA (Kulzer GmbH, Germany) desensitizing agent

Intervention Type OTHER

GLUMA desensitizer is used to reduce tooth sensitivity

Interventions

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GLUMA (Kulzer GmbH, Germany) desensitizing agent

GLUMA desensitizer is used to reduce tooth sensitivity

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Occlusal cavitated caries in maxillary and mandibular first and second molars

Exclusion Criteria

* Occlusal caries with axial or proximal extension
* Teeth with periodontal treatment within last three months
* Teeth with cracks
* Teeth to be taken as abutment for prosthesis
* Patients with psychiatric treatment
* Patients in orthodontic treatment or going to need orthodontic treatment
* Patients under dentin hypersensitivity or using desensitizer treatment
* Patients not willing for post treatment follow up
* Patients having any other teeth with pain or sensitivity symptoms
* Caries excavation with pulp exposure and post treatment sensitivity due to occusal interference in restoration
Minimum Eligible Age

15 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tamil Nadu Dr.M.G.R.Medical University

OTHER

Sponsor Role lead

Responsible Party

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Dr. Geeth Deepika

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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GEETH DEEPIKA, MDS

Role: PRINCIPAL_INVESTIGATOR

TN MGR MEDICAL UNIVERSITY

Locations

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CSI College of Dental Sciences and Research

Madurai, Tamil Nadu, India

Site Status

Countries

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India

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CSICDSR

Identifier Type: -

Identifier Source: org_study_id

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