Selective Enamel Etching in Self-etching Adhesives: a 2-year Clinical Trial

NCT ID: NCT02419157

Last Updated: 2015-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2014-10-31

Brief Summary

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The purpose of this study is to evaluate the clinical effectiveness of non-carious cervical lesions (NCCLs) restored with two self-etching adhesive systems applied with or without selective enamel etching.

Detailed Description

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The purpose of this study is to evaluate the clinical effectiveness of non-carious cervical lesions (NCCLs) restored with two self-etching adhesive systems: Clearfil SE Bond (Kuraray Noritake, Japan) and Xeno V + (Dentsply De Trey, Germany) applied with or without 36% phosphoric acid enamel etching. Assessments were at baseline, 3, 6, 12, 18 and 24 months of clinical service.

Conditions

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Selective Enamel Etching in Dental Restorations

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Clearfil SE Bond Etch (CSE-E)

CSE-E (n=28): After shade selection, teeth were restored under relative isolation. Lesions were cleaned with pumice and water in a rubber cup followed by rinsing and drying. An enamel bevel of 1-2 mm was prepared with a diamond bur operated in a high-speed handpiece under air-water spray. Enamel margins were selectively etched with 36% phosphoric acid for 15s and subsequently thoroughly rinsed and air-dried. Adhesive system was applied according to manufacturers' instructions and light-cured with an LED for 10s. NCCLs were restored incrementally with a microhybrid composite resin. Increments were light cured for 20s. Afterwards, retraction cord was removed and finishing and polishing were performed with rubber points.

Selective enamel etching with 36% phosphoric acid

Group Type ACTIVE_COMPARATOR

Selective enamel etching with 36% phosphoric acid

Intervention Type DRUG

Etch: selective 36% phosphoric acid enamel etching

Clearfil SE Bond

Intervention Type DEVICE

Xeno V+ Etch (XV-E)

XV-E (n=28): After shade selection, teeth were restored under relative isolation. Lesions were cleaned with pumice and water in a rubber cup followed by rinsing and drying. An enamel bevel of 1-2 mm was prepared with a diamond bur operated in a high-speed handpiece under air-water spray. Enamel margins were selectively etched with 36% phosphoric acid for 15s and subsequently thoroughly rinsed and air-dried. Adhesive system was applied according to manufacturers' instructions and light-cured with an LED for 10s. NCCLs were restored incrementally with a microhybrid composite resin. Increments were light cured for 20s. Afterwards, retraction cord was removed and finishing and polishing were performed with rubber points.

Selective enamel etching with 36% phosphoric acid

Group Type ACTIVE_COMPARATOR

Selective enamel etching with 36% phosphoric acid

Intervention Type DRUG

Etch: selective 36% phosphoric acid enamel etching

Xeno V

Intervention Type DEVICE

Clearfil SE Bon Non-etch (CSE-NE)

CSE-NE (n=28): After shade selection, teeth were restored under relative isolation. Lesions were cleaned with pumice and water in a rubber cup followed by rinsing and drying. An enamel bevel of 1-2 mm was prepared with a diamond bur operated in a high-speed handpiece under air-water spray. Adhesive system was applied according to manufacturers' instructions and light-cured with an LED for 10s. NCCLs were restored incrementally with a microhybrid composite resin. Increments were light cured for 20s. Afterwards, retraction cord was removed and finishing and polishing were performed with rubber points.

No selective enamel etching with 36% phosphoric acid

Group Type ACTIVE_COMPARATOR

No selective enamel etching with 36% phosphoric acid

Intervention Type DRUG

Non-etch: without phosphoric acid selective enamel etching

Clearfil SE Bond

Intervention Type DEVICE

Xeno V+ Non-etch (XV-NE)

XV-NE (n=28): After shade selection, teeth were restored under relative isolation. Lesions were cleaned with pumice and water in a rubber cup followed by rinsing and drying. An enamel bevel of 1-2 mm was prepared with a diamond bur operated in a high-speed handpiece under air-water spray. Adhesive system was applied according to manufacturers' instructions and light-cured with an LED for 10s. NCCLs were restored incrementally with a microhybrid composite resin. Increments were light cured for 20s. Afterwards, retraction cord was removed and finishing and polishing were performed with rubber points.

No selective enamel etching with 36% phosphoric acid

Group Type ACTIVE_COMPARATOR

No selective enamel etching with 36% phosphoric acid

Intervention Type DRUG

Non-etch: without phosphoric acid selective enamel etching

Xeno V

Intervention Type DEVICE

Interventions

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Selective enamel etching with 36% phosphoric acid

Etch: selective 36% phosphoric acid enamel etching

Intervention Type DRUG

No selective enamel etching with 36% phosphoric acid

Non-etch: without phosphoric acid selective enamel etching

Intervention Type DRUG

Clearfil SE Bond

Intervention Type DEVICE

Xeno V

Intervention Type DEVICE

Other Intervention Names

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36% phosphoric acid Without 36% phosphoric acid

Eligibility Criteria

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Inclusion Criteria

* Be at least 18 years;
* Present at least 4 NCCLs in vital teeth with margins in enamel and dentin (and its largest area in dentin), independently of teeth location;
* Non-smoking;
* Read and sign the Statement of Informed Consent.

Exclusion Criteria

* Compromised medical history;
* Severe or chronic periodontitis;
* Extreme caries sensitivity;
* Heavy bruxism;
* Under orthodontic treatment;
* Poor oral hygiene;
* Smokers.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Guarulhos

OTHER

Sponsor Role lead

Responsible Party

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Caroline Ely

Associate Faculty

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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André F Reis

Role: PRINCIPAL_INVESTIGATOR

University of Guarulhos

References

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De Munck J, Van Landuyt K, Peumans M, Poitevin A, Lambrechts P, Braem M, Van Meerbeek B. A critical review of the durability of adhesion to tooth tissue: methods and results. J Dent Res. 2005 Feb;84(2):118-32. doi: 10.1177/154405910508400204.

Reference Type BACKGROUND
PMID: 15668328 (View on PubMed)

De Munck J, Vargas M, Iracki J, Van Landuyt K, Poitevin A, Lambrechts P, Van Meerbeek B. One-day bonding effectiveness of new self-etch adhesives to bur-cut enamel and dentin. Oper Dent. 2005 Jan-Feb;30(1):39-49.

Reference Type BACKGROUND
PMID: 15765956 (View on PubMed)

Perdigao J, Geraldeli S. Bonding characteristics of self-etching adhesives to intact versus prepared enamel. J Esthet Restor Dent. 2003;15(1):32-41; discussion 42. doi: 10.1111/j.1708-8240.2003.tb00280.x.

Reference Type BACKGROUND
PMID: 12638771 (View on PubMed)

Peumans M, De Munck J, Van Landuyt K, Lambrechts P, Van Meerbeek B. Five-year clinical effectiveness of a two-step self-etching adhesive. J Adhes Dent. 2007 Feb;9(1):7-10.

Reference Type BACKGROUND
PMID: 17432395 (View on PubMed)

Van Meerbeek B, Kanumilli P, De Munck J, Van Landuyt K, Lambrechts P, Peumans M. A randomized controlled study evaluating the effectiveness of a two-step self-etch adhesive with and without selective phosphoric-acid etching of enamel. Dent Mater. 2005 Apr;21(4):375-83. doi: 10.1016/j.dental.2004.05.008.

Reference Type BACKGROUND
PMID: 15766585 (View on PubMed)

Reis AF, Bedran-Russo AK, Giannini M, Pereira PN. Interfacial ultramorphology of single-step adhesives: nanoleakage as a function of time. J Oral Rehabil. 2007 Mar;34(3):213-21. doi: 10.1111/j.1365-2842.2006.01656.x.

Reference Type BACKGROUND
PMID: 17302950 (View on PubMed)

Cvar JF, Ryge G. Reprint of criteria for the clinical evaluation of dental restorative materials. 1971. Clin Oral Investig. 2005 Dec;9(4):215-32. doi: 10.1007/s00784-005-0018-z. No abstract available.

Reference Type BACKGROUND
PMID: 16315023 (View on PubMed)

Other Identifiers

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PRGRE 2015

Identifier Type: -

Identifier Source: org_study_id

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