Effect of Stent Size on Dyssynchrony

NCT ID: NCT04228874

Last Updated: 2020-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

265 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2019-12-01

Brief Summary

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the effect of stent size and number on left ventricular mechanical dyssynchrony after PCI using drug eluting stent is not clear enough

Detailed Description

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Background: the effect of stent size and number on left ventricular mechanical dyssynchrony after PCI using drug eluting stent is not clear enough Aim: to study short term effect of stent size and number on left ventricular mechanical dyssynchrony after elective PCI to LAD artery.

Patients and methods: the study included 150 adult patients with electively stented LAD lesion with DES. Patients were evaluated pre PCI then follow up at 1m and 3m using tissue synchronization image (TSI).

Conditions

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Left Ventricular Function

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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coronary artery stents

Coronary angiography was done for all the patients according to the Judkins technique. All images were evaluated by an experienced operator, significant coronary artery disease was defined as \> 70 % luminar diameter stenos. The following data was obtained:

* Site of stent implantation within LAD. The first Diagonal branch serves as the boundary between the proximal and mid portion of the LAD. Thus, the portion of the artery prior to the origin of the 1st diagonal is known as the proximal LAD, while the segment just below the1st diagonal branch is the mid LAD. The distal segment of the LAD is the terminal third of the artery (Cao et al., 2017).
* Length, diameter and number of stents.
* TIMI flow after stent deployment.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* adult patients with electively stented LAD lesion with DES were enrolled in the study. Patients were evaluated pre PCI then follow up at 1m and 3m after PCI using TSI.

Exclusion Criteria

* patients with Bundle branch block (BBB),
* Previous percutaneous coronary intervention (PCI),
* Previous coronary artery bypass graft (CABG),
* Rhythm other than sinus,
* Rheumatic heart disease,
* Prosthetic valve,
* Complicated or unsuccessful procedure,
* Patients with significant degenerative changes,
* Patients with previous STEMI,
* and dropped patients from follow up were excluded from the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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shaimaa Mostafa

assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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shaimaa Mostafa

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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dyssynchrony

Identifier Type: -

Identifier Source: org_study_id

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