Dual Arterial Phase Liver CT in Patients With Suspected Portal Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-12-26

Study Completion Date

2022-06-30

Brief Summary

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Patients with liver cirrhosis is at risk of developing HCC. To diagnose or detect HCC at CT/MRI, optimal late arterial phase (LAP) acquisition is critical to capture the tumor. For LAP acquisition, bolus-tracking is often used at CT. In patients with portal hypertension, however, bolus-tracking occasionally capture early arterial phase which may be related with slow portomesenteric flow. In this study, we obtain dual arterial phase in patients with suspected portal hypertension and determine whether this protocol (dual arterial phase) would provide higher incidence of LAP acquisition than single arterial phase acquisition.

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Detailed Description

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Conditions

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HCC Cirrhosis, Liver

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Liver CT with dual arterial phase

Group Type EXPERIMENTAL

Liver CT

Intervention Type DIAGNOSTIC_TEST

Liver CT with precontrast, dual arterial phase, portal venous phase, and delayed phase.

Interventions

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Liver CT

Liver CT with precontrast, dual arterial phase, portal venous phase, and delayed phase.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Older than 20 years
* Liver cirrhosis diagnosed with characteristic imaging feature or histology
* Presence of portal hypertension sign (splenomegaly and varices)
* Scheduled for liver CT
* And signed informed consent