Short-term MRI for Treatment Response Evaluation/Prediction of HCC Treated With TARE

NCT ID: NCT03731910

Last Updated: 2021-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-11

Study Completion Date

2023-06-30

Brief Summary

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This study aims to investigate the value of early change at MRI in HCC treated with TARE, for evaluation/prediction of treatment response and prognosis.

Detailed Description

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Conditions

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Hepatocellular Carcinoma

Keywords

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MRI

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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HCC group

Participants who are scheduled for TARE for HCC treatment. They undergo MRI three times- before, 1- and 2-week after TARE.

Group Type EXPERIMENTAL

MRI

Intervention Type DIAGNOSTIC_TEST

liver MRI using standard dose of extracellular agent. It includes dynamic contrast-enhanced MRI and diffusion weighted image.

Interventions

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MRI

liver MRI using standard dose of extracellular agent. It includes dynamic contrast-enhanced MRI and diffusion weighted image.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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magnetic resonance imaging

Eligibility Criteria

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Inclusion Criteria

* Intermediate or locally advanced HCC according to Hong Kong Liver Cancer guideline
* Scheduled for transarterial radioembolization (TARE)
* sign informed consent

Exclusion Criteria

* Any absolute or relative contra-indication of contrast-enhanced MRI
* History of other local treatment before TARE in 3 weeks
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dongkook Lifesicence

UNKNOWN

Sponsor Role collaborator

Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jeong Min Lee

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jeong Min Lee, MD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Locations

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Seoul National University Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Hyun Hee Lee, RN

Role: CONTACT

Phone: 82-2-2072-4177

Email: [email protected]

Jeong Hee Yoon, MD

Role: CONTACT

Phone: 82-2-2072-2584

Email: [email protected]

Facility Contacts

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Hyun Hee Lee, RN

Role: primary

Jeong Hee Yoon, MD

Role: backup

Other Identifiers

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SNUH-1807-149-957

Identifier Type: -

Identifier Source: org_study_id