Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease

NCT ID: NCT04163484

Last Updated: 2024-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

156 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-15

Study Completion Date

2024-05-30

Brief Summary

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The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors of contrast-induced acute kidney injury development and the influence of contrast-induced kidney injury on 1-year prognosis.

Detailed Description

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Conditions

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Coronary Artery Disease Angina, Unstable Angina, Stable STEMI - ST Elevation Myocardial Infarction NSTEMI - Non-ST Segment Elevation MI Contrast-induced Nephropathy Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Stable coronary artery disease

Iodinated contrast

Intervention Type OTHER

Intra-arterial injection of iodinated contrast media during percutaneous coronary intervention

ST-elevation myocardial infarction

Iodinated contrast

Intervention Type OTHER

Intra-arterial injection of iodinated contrast media during percutaneous coronary intervention

Non-ST-elevation myocardial infarction

Iodinated contrast

Intervention Type OTHER

Intra-arterial injection of iodinated contrast media during percutaneous coronary intervention

Interventions

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Iodinated contrast

Intra-arterial injection of iodinated contrast media during percutaneous coronary intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Males and females aged 18-80
* Stable CAD receiving optimal medical treatment requiring PCI or STEMI or NSTEMI
* Intra-arterial injection of iodinated contrast media
* Informed consent

Exclusion Criteria

* Age less than 18
* Pregnancy, lactation
* Refuse to sign the informed consent
* Contraindications for PCI
* Other conditions affecting prognosis (oncology, liver failure etc)
* CKD stage 4-5
* Patients receiving nephrotoxic drugs
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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I.M. Sechenov First Moscow State Medical University

OTHER

Sponsor Role lead

Responsible Party

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Olga Mironova

MD PhD Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Olga Mironova, MD PhD

Role: STUDY_DIRECTOR

I. M. Sechenov First Moscow State Medical University (Sechenov University)

Locations

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Sechenov University

Moscow, , Russia

Site Status

Countries

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Russia

Related Links

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http://doi.org/10.26442/20751753.2022.10.201925

Kuznetsov VA, Mironova OIu, Gritsanchuk AM, Fomin VV. Contrast-associated acute kidney injury after percutaneous coronary interventions in patients with acute coronary syndrome: a real-world study. Consilium Medicum. 2022;24(10):713-717

Other Identifiers

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11/2019

Identifier Type: -

Identifier Source: org_study_id

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