Single-cycle Remote Ischemic Preconditioning and Postconditioning for Prevention of Contrast-Induced Nephropathy
NCT ID: NCT02729155
Last Updated: 2018-08-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
596 participants
INTERVENTIONAL
2015-10-31
2020-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
PREVENTION
TRIPLE
Study Groups
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RIPre + RIPost
Intervention: RIPre 200 mmHg + RIPost 200 mmHg
RIPre
Preconditioning 200 mmHg x 5 minutes before procedure
RIPost
Postconditioning 200 mmHg x 5 minutes after procedure
RIPre + Sham
Intervention: RIPre 200 mmHg + Sham 10 mmHg
RIPre
Preconditioning 200 mmHg x 5 minutes before procedure
Sham-Post
Sham 10 mmHg x 5 minutes after procedure
Sham + RIPost
Intervention: Sham 10 mmHg + RIPost 200 mmHg
RIPost
Postconditioning 200 mmHg x 5 minutes after procedure
Sham-Pre
Sham 10 mmHg x 5 minutes before procedure
Sham + Sham
Intervention: Sham 10 mmHg + Sham 10 mmHg
Sham-Pre
Sham 10 mmHg x 5 minutes before procedure
Sham-Post
Sham 10 mmHg x 5 minutes after procedure
Interventions
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RIPre
Preconditioning 200 mmHg x 5 minutes before procedure
RIPost
Postconditioning 200 mmHg x 5 minutes after procedure
Sham-Pre
Sham 10 mmHg x 5 minutes before procedure
Sham-Post
Sham 10 mmHg x 5 minutes after procedure
Eligibility Criteria
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Inclusion Criteria
* Impaired renal function with reduced eGFR \< 60 ml/min/1.73 m2 by CKD-EPI equation.
* Written informed consent.
Exclusion Criteria
* The patient had end-stage renal failure with the need for hemodialysis.
* The patient take medications that affect the kidneys function within 48 hours before study.
* The patient had acute kidney injury from any cause.
* The patient was received contrast media within 2 weeks before study.
* The patient had cardiac arrest or shock.
* The patient had peripheral arterial disease (PAD)
* Pregnancy
* Refused to study
ALL
No
Sponsors
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Phramongkutklao College of Medicine and Hospital
OTHER
Responsible Party
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Col. Suthee Panichkul
Phramongkutklao College of Medicine and Hospital
Principal Investigators
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Nakarin Sansanayudh, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Phramongkutklao College of Medicine and Hospital
Locations
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Department of Internal Medicine
Bangkok, , Thailand
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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PMK-SCRIP-CIN
Identifier Type: -
Identifier Source: org_study_id
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