Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts

NCT ID: NCT04158284

Last Updated: 2024-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-01

Study Completion Date

2024-06-30

Brief Summary

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KRANIOPHARYNGEOM Registry 2019 will prospectively collect and descriptively analyse data on diagnostics, treatment, and follow-up of patients with craniopharyngioma. In continuation of preceding studies also patients with xanthogranuloma, meningioma, pituitary adenoma, prolactinoma and cystic intracranial malformations will be registered.

Detailed Description

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Conditions

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Craniopharyngioma Obesity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Diagnosed with craniopharyngioma for the first time
2. Age at diagnosis 18 years or less of age
3. Agreement from patient's parents or legal guardian as well as the patient

Exclusion Criteria

1. Age at diagnosis over 18 years of age
2. Diagnosis different from craniopharyngioma
Minimum Eligible Age

1 Day

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Society for Pediatric Oncology and Hematology GPOH gGmbH

OTHER

Sponsor Role collaborator

Deutsche Gesellschaft für Kinderendokrinologie und Diabetologie (DGKED)

UNKNOWN

Sponsor Role collaborator

Deutsche Gesellschaft für Endokrinologie (DGE)

UNKNOWN

Sponsor Role collaborator

Arbeitsgemeinschaft Pädiatrische Radioonkologie (APRO)

UNKNOWN

Sponsor Role collaborator

Deutschen Gesellschaft für Radioonkologie (DEGRO)

UNKNOWN

Sponsor Role collaborator

Klinikum Oldenburg gGmbH

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. med. Hermann Mueller

Professor MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Klinikum Oldenburg

Oldenburg, Lower Saxony, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Hermann L Mueller, MD

Role: CONTACT

+49 441 403 ext. 2013

Svenja Boekhoff

Role: CONTACT

+49 441 403 ext. 2072

Facility Contacts

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Hermann L Mueller, MD

Role: primary

+49 441 403 ext. 2013

Svenja Boekhoff

Role: backup

+49 441 403 ext. 2072

References

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Sowithayasakul P, Beckhaus J, Ozyurt J, Bison B, Friedrich C, Muller HL. Prolactin serum concentrations in childhood-onset craniopharyngioma patients. J Endocrinol Invest. 2025 Sep;48(9):2041-2051. doi: 10.1007/s40618-025-02622-4. Epub 2025 Jun 7.

Reference Type DERIVED
PMID: 40481916 (View on PubMed)

Mann-Markutzyk LV, Beckhaus J, Ozyurt J, Mehren A, Friedrich C, Muller HL. Daytime sleepiness and health-related quality of life in patients with childhood-onset craniopharyngioma. Sci Rep. 2025 Mar 19;15(1):9407. doi: 10.1038/s41598-025-94384-5.

Reference Type DERIVED
PMID: 40108339 (View on PubMed)

Wagener K, Beckhaus J, Boekhoff S, Friedrich C, Muller HL. Sporadic and neurofibromatosis type 2-associated meningioma in children and adolescents. J Neurooncol. 2023 Jul;163(3):555-563. doi: 10.1007/s11060-023-04344-0. Epub 2023 Jul 4.

Reference Type DERIVED
PMID: 37402092 (View on PubMed)

Beckhaus J, Friedrich C, Boekhoff S, Calaminus G, Bison B, Eveslage M, Timmermann B, Flitsch J, Muller HL. Outcome after pediatric craniopharyngioma: the role of age at diagnosis and hypothalamic damage. Eur J Endocrinol. 2023 Mar 2;188(3):lvad027. doi: 10.1093/ejendo/lvad027.

Reference Type DERIVED
PMID: 36857103 (View on PubMed)

Other Identifiers

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KRANIOPHARYNGEOM Registry 2019

Identifier Type: -

Identifier Source: org_study_id

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