A Twenty-years' Experience in Pituitary Disease.

NCT ID: NCT06973824

Last Updated: 2025-05-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-10

Study Completion Date

2028-04-30

Brief Summary

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Pituitary tumors represent a heterogeneous group of neoplasms by histotype. The pituitary adenomas are the most frequent heteroformation, among those affecting the pituitary gland, followed by meningiomas, craniopharyngiomas, germosomes and tumours secondary, such as metastases and lymphomas. Since these conditions are considered rare, the data epidemiology and prognosis to predict the natural history of these diseases can not be considered conclusive. Pituitary adenomas are a useful model for epidemiology in the study of pathology pituitary. Over the past 20 years, several attempts have been made to identify unique prognostic factors, which predict the outcome of these pathologies, but without To arrive at a definitive classification. The purpose of this study aims to collect clinical, biochemical, morphological and pathological data on the retrospective and prospective cohort of over 1600 patients undergoing neurosurgical removal of pituitary tumors in the last 20 years, to develop a prognostic classification.

Detailed Description

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Conditions

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Pituitary Adenoma Pituitary Cancer Pituitary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Patients with pituitary tumors

Patients with pituitary tumors, underwent surgical resection

Frequency of disease recurrence

Intervention Type OTHER

To collect data of pituitary disease recurrence

Interventions

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Frequency of disease recurrence

To collect data of pituitary disease recurrence

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients underwent surgery for pituitary tumors;
* pathology diagnosis of pituitary tumors;
* patients older then 18 years at diagnosis of pituitary tumors;
* 2 years follow-up;

Exclusion Criteria

* age lower then 18 years
* follow-up shorter than 2 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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Doglietto Francesco

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Francesco Doglietto, Prof

Role: PRINCIPAL_INVESTIGATOR

Fondazione Policlinico Universitario A. Gemelli, IRCCS

Locations

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Fondazione Policlinico Gemelli IRCCS

Rome, IT, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Francesco Doglietto, Prof

Role: CONTACT

+390630155701

Sabrina Chiloiro, MD

Role: CONTACT

Other Identifiers

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6546

Identifier Type: -

Identifier Source: org_study_id

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