Efficacy of the Memory Motivation (MEMO) Web Application Training

NCT ID: NCT04142801

Last Updated: 2019-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

49 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-05

Study Completion Date

2019-08-10

Brief Summary

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Memory, attentional, and behavioural symptoms are the clinical hallmarks of Neurocognitive disorders (NCD) such as Alzheimer's disease and related disorders. The World Health Organisation (WHO) guidelines for risk reduction of cognitive decline and dementia indicate that Cognitive training may be offered to older adults with normal cognition and with mild cognitive impairment to reduce the risk of cognitive decline and/or dementia. The use of Information and Communication Technologies (ICT) in the health domain is progressively expanding. The Alzheimer Innovation Association have developed MeMo (Memory Motivation) a free web application that can be used at home by patients.

The objective of the present study was to assess the effectiveness of employing the MeMo platform on cognitive performance in patients suffering from NCD.

Detailed Description

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The objective of this study is to evaluate the effectiveness of the MeMo cognitive training exercise platform in patients suffering from neurocognitive disorders. These exercises ,have been developed by the association Innovation Alzheimer and the CoBTeK research team, located with the Nice memory Center at the Institut Claude Pompidou. MeMo can be used freely at home by patients. More specifically, it is a randomized controlled study that aims to compare the evolution of activities cognition and behavior between patients not using these exercises, and patients using these exercises for 12 weeks, 4 sessions per week.

Conditions

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Neurocognitive Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

regular use of a web application at home to train cognition and behavior
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Randomization for the allocation of the patient in each group

Study Groups

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MeMo group

MeMo group: experimental: regular use at home of the Memo web application In the Memo group patients were instructed on how to use the application, and allowed to train for 12 weeks. It was also explained that this training needed to be done regularly on a basis of 4 sessions of 30 minutes each per week.

Group Type EXPERIMENTAL

MeMo web application

Intervention Type DEVICE

The patient betwenn 2 consultation could use the application MeMo. MeMo is a web application that can thus be used on any web browser (computer or tablet). On tablet, the application can be installed on home screen to look like a native app, and used offline.

Control group

Regular follow up at the memory center without cognitive training

Group Type PLACEBO_COMPARATOR

Control group

Intervention Type OTHER

the patient have the classical follow up at the memory center (consultation)

Interventions

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MeMo web application

The patient betwenn 2 consultation could use the application MeMo. MeMo is a web application that can thus be used on any web browser (computer or tablet). On tablet, the application can be installed on home screen to look like a native app, and used offline.

Intervention Type DEVICE

Control group

the patient have the classical follow up at the memory center (consultation)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Outpatient consulting the Memory center
* older than 60 years old
* Mini Mental State examination score (MMSE) between 16 and 28 / 30
* met the DSM 5 diagnoses of mild neurocognitive disorders (mild NCD) or major neurocognitive disorders (Major NCD).

Exclusion Criteria

* Patients not able to read and write French
* presence of a hearing or major visual impairment
* a history of premorbid mental retardation
* had already used the MeMo application
* were presently involved in structured memory training activities.
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alzheimer's Association

OTHER

Sponsor Role collaborator

Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role collaborator

Université de Nice Sophia Antipolis

OTHER

Sponsor Role collaborator

Innovation Alzheimer

OTHER

Sponsor Role lead

Responsible Party

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Philippe robert, MD, PhD

Professor of Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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CoBtek lab, Institut Claude Pompidou

Nice, , France

Site Status

Countries

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France

References

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Robert P, Manera V, Derreumaux A, Ferrandez Y Montesino M, Leone E, Fabre R, Bourgeois J. Efficacy of a Web App for Cognitive Training (MeMo) Regarding Cognitive and Behavioral Performance in People With Neurocognitive Disorders: Randomized Controlled Trial. J Med Internet Res. 2020 Mar 11;22(3):e17167. doi: 10.2196/17167.

Reference Type DERIVED
PMID: 32159519 (View on PubMed)

Other Identifiers

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2016-A00879-42

Identifier Type: -

Identifier Source: org_study_id

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