Exercise Training as Medicine for Substance Use Disorder Patients

NCT ID: NCT04065334

Last Updated: 2025-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

171 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2023-12-11

Brief Summary

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This study compares the effects of high dose and low dose, high intensity, endurance training and strength training in substance use disorder patients. The hypothesis is that the increase in endurance (measured as maximal oxygen uptake) and strength (measured as maximal strength) will be similar in both the high dose and low dose training groups after 24 training sessions over eight weeks. The rationale for this assumption is based on the patient groups poor physical capacity, supporting that a lesser physical workload is needed to achieve a substantial increase in physical capacity. The practical implication could be higher training attendance, because it is likely easier to motivate the patient group when they only have to perform half the workload. It is paramount for this patient group to increase their physical capacity and consequently augment their physical health status since they are in a high-risk group for developing life-threatening lifestyle related diseases.

Detailed Description

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Conditions

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Substance Use Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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low dose training

Group Type EXPERIMENTAL

low dose training

Intervention Type BEHAVIORAL

1 x 4 minutes of high intensity workload on treadmill and 2 repetitions x 4 sets of high intensity workload in hack squat

high dose training

Group Type ACTIVE_COMPARATOR

High dose training

Intervention Type BEHAVIORAL

4 x 4 minutes of high intensity workload on treadmill and 4 repetitions x 4 sets of high intensity workload in hack squat

Interventions

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High dose training

4 x 4 minutes of high intensity workload on treadmill and 4 repetitions x 4 sets of high intensity workload in hack squat

Intervention Type BEHAVIORAL

low dose training

1 x 4 minutes of high intensity workload on treadmill and 2 repetitions x 4 sets of high intensity workload in hack squat

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Being an inpatient at the clinic
* Free of known cardiovascular disease, pulmonary disease and cancer

Exclusion Criteria

* Not able to perform a maximal treadmill test
* Not able to perform a maximal strength test in hack squat
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Norwegian University of Science and Technology

OTHER

Sponsor Role collaborator

St. Olavs Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kristin Smedsrud

Role: STUDY_DIRECTOR

St. Olavs Hospital

Locations

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Klinikk for rus- og avhengighetsmedisin, St Olavs Hospital

Trondheim, , Norway

Site Status

Countries

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Norway

References

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Loe H, Mosti MP, Wisloff U, Haberstroh C, Flemmen G. Cardiopulmonary and muscular effects of different doses of high-intensity physical training in substance use disorder patients: study protocol for a block allocated controlled endurance and strength training trial in an inpatient setting. BMJ Open. 2022 Sep 27;12(9):e061014. doi: 10.1136/bmjopen-2022-061014.

Reference Type DERIVED
PMID: 36167363 (View on PubMed)

Other Identifiers

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2019/502

Identifier Type: -

Identifier Source: org_study_id

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