Registry for Longitudinal Mortality and Therapy in Patients With Heart Failure

NCT ID: NCT04062500

Last Updated: 2020-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

10500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2027-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this registry is to compile a large clinical database on the medical management of patients hospitalized with acute heart failure, using information collected from hospitals across China.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Registry for Longitudinal mortality and therapy in patients with Heart Failure is a large, multicenter, prospective, open-label registry of the management of patients treated in the hospital for acute heart failure in China. The objective of this study is to investigate the clinical features and prognosis of patients with heart failure, and discover the characteristics of high-risk heart failure patients, and elucidate critical factors which predict the development and outcomes of symptomatic heart failure patients.

1. To elucidate the clinical characteristics and prognostic risks of patients with heart failure.
2. To study the characteristics of high-risk heart failure patients and predict the key factors for the development of symptomatic heart failure patients.
3. To elucidate the compliance of patients with heart failure and the incidence of adverse drug effects.
4. To investigate the effect of self-management on outcomes in patients with heart failure.
5. To elucidate critical factors associated with the development and outcomes of heart failure.
6. To investigate hospitalization expenses for heart failure.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Heart Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with heart failure

patients treated in the hospital for acute heart failure in China

Mortality and Rehospitalization rate

Intervention Type OTHER

Mortality and Re-hospitalization of acute decompensated heart failure

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Mortality and Rehospitalization rate

Mortality and Re-hospitalization of acute decompensated heart failure

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

\- 1. 18 years and older. 2. Meet the diagnostic criteria of China 2018 or JACC/AHA 2017 or ESC 2016 heart failure guidelines.

3\. Agree to be tested and sign an informed consent certificate.

Exclusion Criteria

* 1\. Age\<18 years old. 2. Patients who refused to participate. 3. Patients may have a life expectancy of less than 1 years due to non- heart failure clinical conditions.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

First Affiliated Hospital, Sun Yat-Sen University

OTHER

Sponsor Role collaborator

Nanfang Hospital, Southern Medical University

OTHER

Sponsor Role collaborator

Beijing Chao Yang Hospital

OTHER

Sponsor Role collaborator

First Hospital of China Medical University

OTHER

Sponsor Role collaborator

Yangpu District Central Hospital Affiliated to Tongji University

OTHER

Sponsor Role collaborator

Xuhui Central Hospital, Shanghai

OTHER

Sponsor Role collaborator

Ningbo Medical Center Lihuili Hospital

OTHER_GOV

Sponsor Role collaborator

Shaanxi University of Chinese Medicine

OTHER

Sponsor Role collaborator

People's Hospital of Xinjiang Uygur Autonomous Region

OTHER

Sponsor Role collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

Sponsor Role collaborator

Shanghai 10th People's Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Ya-Wei Xu

MD, pHD, Director of Cardiovascular Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Dachun Xu, PhD

Role: PRINCIPAL_INVESTIGATOR

Shanghai Tenthth People's Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Shanghai Tenth People's Hospital, Tongji University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Dachun Xu, PhD

Role: CONTACT

18917684045 ext. +86

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Dachun Xu, MD,PhD

Role: primary

+86 18917684045

Yawei Xu, MD,PhD

Role: backup

+86 13916698181

References

Explore related publications, articles, or registry entries linked to this study.

Su Y, Ma M, Zhang H, Pan X, Zhang X, Zhang F, Lv Y, Yan C. Prognostic value of serum hyponatremia for outcomes in patients with heart failure with preserved ejection fraction: An observational cohort study. Exp Ther Med. 2020 Nov;20(5):101. doi: 10.3892/etm.2020.9231. Epub 2020 Sep 17.

Reference Type DERIVED
PMID: 32973950 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

GREARTWAL

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

National Heart Failure Registry
NCT06683001 RECRUITING
Heart Failure Patients Registry
NCT04709263 COMPLETED
Heart Failure Registry
NCT00530426 COMPLETED