Prognosis of Heart Transplanted Patients With Heart Failure

NCT ID: NCT05775432

Last Updated: 2024-07-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-23

Study Completion Date

2042-12-31

Brief Summary

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Heart transplantation is the most effective treatment for end-stage heart failure, advanced cardiomyopathy, and complex congenital heart disease with severe heart failure or hypoxia. Several clinical studies have shown significant differences in the prognosis of heart transplantation patients with different etiologies, and post-transplantation complications are an important factor affecting patient survival, and there is still a lack of overall prognostic stratification and extensive clinical studies on risk factors after heart transplantation. Therefore, this study is intended to include patients who underwent heart transplantation for different etiologies of heart failure, collect clinical data and biological samples from patients, and use various techniques to deeply interpret the risk factors affecting the prognosis of heart transplantation patients and construct a prognostic prediction model to provide specific and individualized treatment ideas and theoretical basis for improving the survival rate of patients after heart transplantation.

Detailed Description

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Conditions

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Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Heart transplantation group

Patients with heart failure of different etiologies undergoing heart transplant.

No interventions assigned to this group

Control group

Individuals whose hearts are donated.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with end-stage heart failure presented to our hospital who are evaluated by clinicians and ethically approved for heart transplantation
* Individuals whose hearts are donated

Exclusion Criteria

* Patients refuse to sign informed consent form
Minimum Eligible Age

3 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital Xi'an Jiaotong University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guoliang Li

Role: PRINCIPAL_INVESTIGATOR

First Affiliated Hospital Xi'an Jiaotong University

Yang Yan

Role: PRINCIPAL_INVESTIGATOR

First Affiliated Hospital Xi'an Jiaotong University

Locations

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First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Guoliang Li

Role: CONTACT

+8613759982523

Yang Yan

Role: CONTACT

+862985323865

Facility Contacts

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Guoliang Li

Role: primary

Yang Yan

Role: backup

+862985323865

Other Identifiers

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XJTU1AF2023LSK-391

Identifier Type: -

Identifier Source: org_study_id

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