A Retrospective Breast Reconstruction Study

NCT ID: NCT04060134

Last Updated: 2024-02-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

223 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-11-20

Study Completion Date

2022-06-01

Brief Summary

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To collect data on patients who have previously undergone breast reconstruction utilizing SimpliDerm and other HADMs.

Detailed Description

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This study is a retrospective, multi-center, open label study evaluating SimpliDerm and other human acellular dermal matrices in breast reconstruction.

A total of up to 300 patients who underwent direct to implant (one stage) or two-stage unilateral or bilateral breast reconstruction with SimpliDerm an other HADMs at the time of implant or TE placement.

Data will be collected for a minimum of one post-surgical visit after direct implant or exchange. If more visits are available, data from those visits will be collected as well.

Conditions

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Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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SimpliDerm HADM

Patients who had SimpliDerm human acellular dermal matrix used in their breast reconstruction procedure.

SimpliDerm HADM

Intervention Type OTHER

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

AlloDerm HADM

Patients who had AlloDerm human acellular dermal matrix used in their breast reconstruction procedure.

AlloDerm HADM

Intervention Type OTHER

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

AlloMax HADM

Patients who had AlloMax human acellular dermal matrix used in their breast reconstruction procedure.

AlloMax HADM

Intervention Type OTHER

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

FlexHD HADM

Patients who had FlexHD human acellular dermal matrix used in their breast reconstruction procedure.

FlexHD HADM

Intervention Type OTHER

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

DermACELL HADM

Patients who had DermACELL human acellular dermal matrix used in their breast reconstruction procedure.

DermACELL HADM

Intervention Type OTHER

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Interventions

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SimpliDerm HADM

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Intervention Type OTHER

AlloDerm HADM

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Intervention Type OTHER

AlloMax HADM

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Intervention Type OTHER

FlexHD HADM

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Intervention Type OTHER

DermACELL HADM

Human acellular dermal matrices are used for the repair or replacement of damaged or inadequate integumental tissue or for other homologous uses of human integument.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female patient who underwent immediate breast reconstruction post-mastectomy; either direct to implant or with a tissue expander followed by exchange for a saline or gel implant.
* HADMs such as: InteguPly, SimpliDerm, AlloDerm, FlexHD, DermACELL, Cortiva, or AlloMax used in the breast reconstruction.

Exclusion Criteria

* Female patient who underwent cosmetic/aesthetic breast augmentation procedure or revision.
* Female patient who underwent delayed breast reconstruction procedure.
* Female patient who underwent revision of previous breast reconstruction procedure.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Elutia Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Baptist Medical Center South

Montgomery, Alabama, United States

Site Status

Shoals Plastic Surgery

Muscle Shoals, Alabama, United States

Site Status

Tierney Plastic Surgery

Nashville, Tennessee, United States

Site Status

Ascension/Seton Institute of Reconstructive Plastic Surgery

Austin, Texas, United States

Site Status

DHR Health

McAllen, Texas, United States

Site Status

Countries

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United States

Related Links

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http://www.aziyo.com

Aziyo Biologics, Inc.

Other Identifiers

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CLP-0004

Identifier Type: -

Identifier Source: org_study_id

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