Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction

NCT ID: NCT02263261

Last Updated: 2018-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-11-30

Brief Summary

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Use of a HADM and implant in post-mastectomy breast reconstruction.

Detailed Description

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This is a prospective, single-site pilot study in which outcomes associated with the use of Flex HD® Pliable™ Perforated, Human Acellular Dermal Matrix and an implant which are used in post-mastectomy breast reconstruction will be obtained. The data collected will include reconstructive outcomes, aesthetic outcomes and patient-reported outcomes in order to ascertain advantages and disadvantages of using this particular HADM in post-mastectomy breast reconstruction.

Conditions

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Mastectomy Breast Reconstruction

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Flex HD Pliable Perforated HADM

Single Arm

Group Type OTHER

Flex HD Pliable Perforated HADM

Intervention Type OTHER

Human Acellular Dermal Matrix

Interventions

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Flex HD Pliable Perforated HADM

Human Acellular Dermal Matrix

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Scheduled to undergo a single or two-stage, tissue-assisted, implant breast reconstruction
* Mastectomy may be unilateral or bilateral, prophylactic or therapeutic
* Skin incision may be skin sparing, or nipple-areolar sparing
* Have signed written, informed consent
* Be at least 18 years of age

Exclusion Criteria

* Patients undergoing autologous breast reconstruction
* Patients undergoing breast reconstruction following complications of breast augmentation, mastopexy, breast reduction, or breast conservation surgery (lumpectomy)
* Patients undergoing reconstruction after previously failed attempts at reconstruction
* Patients undergoing autologous breast reconstruction in conjunction with a tissue expander (such as a latissimus dorsi flap, DIEP flap)
* There will be no exclusions based on race or ethnicity
* BMI \> 40
* Previous Radiation Treatment. Note: Post-operative radiation treatment does not exclude subjects from study continuation once enrolled.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Musculoskeletal Transplant Foundation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Liu Plastic surgery

Mountain View, California, United States

Site Status

Liu Plastic Surgery

San Jose, California, United States

Site Status

Countries

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United States

Other Identifiers

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MTF 13-03

Identifier Type: -

Identifier Source: org_study_id

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