Study Results
Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.
View full resultsBasic Information
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COMPLETED
NA
2905455 participants
INTERVENTIONAL
2019-07-23
2024-05-20
Brief Summary
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Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Routine cluster detection
Hospitals will use routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Routine cluster detection
Hospitals will use routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Enhanced cluster detection
Hospitals will use an automated statistical cluster detection tool in addition to routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Enhanced cluster detection
Hospitals will use an automated statistical cluster detection tool in addition to routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Interventions
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Routine cluster detection
Hospitals will use routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Enhanced cluster detection
Hospitals will use an automated statistical cluster detection tool in addition to routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Eligibility Criteria
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Inclusion Criteria
* Facilities that are reporting to the centralized data warehouse during the study period.
Exclusion Criteria
Note: unit of randomization is the hospital.
ALL
No
Sponsors
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Hospital Corporation of America
INDUSTRY
Brigham and Women's Hospital
OTHER
University of California, Irvine
OTHER
Harvard School of Public Health (HSPH)
OTHER
Rush University
OTHER
Duke University
OTHER
University of Massachusetts, Amherst
OTHER
University of California, San Francisco
OTHER
Cook County Health & Hospitals System
OTHER
Centers for Disease Control and Prevention
FED
Harvard Pilgrim Health Care
OTHER
Responsible Party
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Richard Platt
Professor and Department Chair
Principal Investigators
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Richard Platt, MD, MSc
Role: PRINCIPAL_INVESTIGATOR
Harvard Pilgrim Health Care Institute
Susan Huang, MD, MPH
Role: PRINCIPAL_INVESTIGATOR
University of California, Irvine
Meghan Baker, MD, ScD
Role: STUDY_DIRECTOR
Brigham and Women's Hospital
Locations
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Riverside Community Hospital
Riverside, California, United States
Regional Medical Center of San Jose
San Jose, California, United States
Los Robles Regional Medical Center
Thousand Oaks, California, United States
Swedish Medical Center
Denver, Colorado, United States
Sky Ridge Medical Center
Denver, Colorado, United States
Presbyterian St. Luke's Medical Center
Denver, Colorado, United States
Rose Medical Center
Denver, Colorado, United States
North Suburban Medical Center - JV
Thornton, Colorado, United States
JFK Medical Center
Atlantis, Florida, United States
Brandon Regional
Brandon, Florida, United States
Lawnwood Regional Medical Center
Ft. Pierce, Florida, United States
Memorial Hospital Jacksonville
Jacksonville, Florida, United States
Lake City Medical Center
Lake City, Florida, United States
Largo Medical Center
Largo, Florida, United States
Ocala Regional Medical Center
Ocala, Florida, United States
West Marion Community Hospital
Ocala, Florida, United States
Raulerson Hospital
Okeechobee, Florida, United States
Orange Park Medical Center
Orange Park, Florida, United States
Gulf Coast Medical Center
Panama City, Florida, United States
West Florida Hospital
Pensacola, Florida, United States
Fawcett Memorial Hospital
Port Charlotte, Florida, United States
St. Lucie Medical Center
Port Saint Lucie, Florida, United States
Central Florida Regional Hospital
Sanford, Florida, United States
Doctor's Hospital Sarasota
Sarasota, Florida, United States
Northside Hospital
St. Petersburg, Florida, United States
South Bay Hospital
Sun City Center, Florida, United States
Medical Center of Trinity
Trinity, Florida, United States
JFK Medical Center - North Campus
West Palm Beach, Florida, United States
Fairview Park
Dublin, Georgia, United States
Redmond Regional Medical Center
Rome, Georgia, United States
Eastside Medical Center
Snellville, Georgia, United States
West Valley Medical Center
Caldwell, Idaho, United States
Eastern Idaho Regional
Idaho Falls, Idaho, United States
Menorah Medical Center
Overland Park, Kansas, United States
Overland Park Regional Medical Center
Overland Park, Kansas, United States
Wesley Medical Center
Wichita, Kansas, United States
Wesley Woodlawn Hospital
Wichita, Kansas, United States
Greenview Regional Hospital
Bowling Green, Kentucky, United States
Garden Park Medical Center
Gulfport, Mississippi, United States
Research Medical Center
Kansas City, Missouri, United States
Lee's Summit Medical Center
Lee's Summit, Missouri, United States
Mountainview Hospital - Vegas
Las Vegas, Nevada, United States
Parkland Medical Center
Derry, New Hampshire, United States
Portsmouth Regional Hospital
Portsmouth, New Hampshire, United States
Spotsylvania Regional Medical Center
Fredericksburg, Pennsylvania, United States
Trident Regional Medical Center
Charleston, South Carolina, United States
Grand Strand Regional Medical Center
Myrtle Beach, South Carolina, United States
Summerville Medical Center
Summerville, South Carolina, United States
Colleton Medical Center
Walterboro, South Carolina, United States
TriStar Horizon Medical Center
Dickson, Tennessee, United States
Summit Medical Center
Hermitage, Tennessee, United States
Centennial Medical Center
Nashville, Tennessee, United States
Southern Hills Medical Center
Nashville, Tennessee, United States
Medical City Arlington
Arlington, Texas, United States
St. David's Medical Center
Austin, Texas, United States
Heart Hospital of Austin
Austin, Texas, United States
Valley Regional Medical Center
Brownsville, Texas, United States
Conroe Regional Medical Center
Conroe, Texas, United States
Medical City Dallas Hospital
Dallas, Texas, United States
Medical City Denton
Denton, Texas, United States
Las Palmas Medical Center
El Paso, Texas, United States
Medical City Fort Worth
Fort Worth, Texas, United States
Medical City Alliance
Fort Worth, Texas, United States
St. David's Georgetown Hospital
Georgetown, Texas, United States
Kingwood Medical Center
Kingwood, Texas, United States
Medical Center of Lewisville
Lewisville, Texas, United States
Rio Grande Regional Hospital
McAllen, Texas, United States
Medical City McKinney
McKinney, Texas, United States
Medical City North Hills
North Richland Hills, Texas, United States
Methodist Hospital
San Antonio, Texas, United States
Methodist Stone Oak Hospital
San Antonio, Texas, United States
Northeast Methodist Hospital
San Antonio, Texas, United States
Mainland Medical Center
Texas City, Texas, United States
Clearlake Regional Medical Center
Webster, Texas, United States
Ogden Regional Medical Center
Ogden, Utah, United States
LewisGale Hospital - Montgomery
Blacksburg, Virginia, United States
Reston Hospital
Reston, Virginia, United States
Retreat Doctors' Hospital
Richmond, Virginia, United States
CJW Medical Center (Chippenham Campus)
Richmond, Virginia, United States
CJW Medical Center (Johnston Willis Campus)
Richmond, Virginia, United States
Henrico Doctors' Hospital - Forest Campus
Richmond, Virginia, United States
Henrico Doctors' Hospital - Parham Campus
Richmond, Virginia, United States
Countries
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References
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Baker MA, Septimus E, Kleinman K, Moody J, Sands KE, Varma N, Isaacs A, McLean LE, Coady MH, Blanchard EJ, Poland RE, Yokoe DS, Stelling J, Haffenreffer K, Clark A, Avery TR, Sljivo S, Weinstein RA, Smith KN, Carver B, Meador B, Lin MY, Lewis SS, Washington C, Bhattarai M, Shimelman L, Kulldorff M, Reddy SC, Jernigan JA, Perlin JB, Platt R, Huang SS. A Trial of Automated Outbreak Detection to Reduce Hospital Pathogen Spread. NEJM Evid. 2024 May;3(5):EVIDoa2300342. doi: 10.1056/EVIDoa2300342. Epub 2024 Apr 23.
Provided Documents
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Document Type: Study Protocol
Document Type: Statistical Analysis Plan
Other Identifiers
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PH000599B
Identifier Type: -
Identifier Source: org_study_id
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