The Link Between Periodontitis, Smoking and Oral Cancer
NCT ID: NCT04047212
Last Updated: 2021-06-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
200 participants
OBSERVATIONAL
2021-08-12
2032-01-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Changes in the oral mucosa arise by primary products resulting from tissue breakdown due to gingivitis. It then triggers the host cells to produce proteinases that mediate loss of marginal periodontal ligaments, apical migration of the junctional epithelium and apical spread of bacterial biofilm.
Therefore, this research aims to identify the risk of smoking to both periodontitis and oral cancer, and the risk of periodontitis to oral cancer.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Metagenomic Analysis of the Link Between Periodontitis and Smoking: Case-control Study
NCT05995158
Correlation Between Periodontitis and Hypertension Among a Sample of Adult Egyptian Patients
NCT04634734
Frequency of Periodontal Disease in Head and Neck Cancer Patients After Radiation Therapy
NCT06667362
Evaluation of the 1999 and 2018 Periodontal Disease Classifications: a Retrospective Study
NCT04815772
Prevalence of Periodontitis in Sample of Egyptian Population
NCT05317208
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Smokers
biopsy for oral cancer
surgical biopsy is to be taken for diagnosis of oral cancer or premalignant lesions
periodontal examination
Periodontal clinical examination to all by periodontal charting
non-Smokers
biopsy for oral cancer
surgical biopsy is to be taken for diagnosis of oral cancer or premalignant lesions
periodontal examination
Periodontal clinical examination to all by periodontal charting
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
biopsy for oral cancer
surgical biopsy is to be taken for diagnosis of oral cancer or premalignant lesions
periodontal examination
Periodontal clinical examination to all by periodontal charting
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Pregnant females.
* Handicapped and mentally retarded patients.
* Patients undergoing radiotherapy.
* Patients having oral cancer
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Cairo University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Ayat Gamal-AbdelNaser
Principal investigator
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Cairo University
Cairo, , Egypt
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
P12
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.