Effect of ctDCS During Balance Training on Cerebellar Ataxia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-30

Study Completion Date

2020-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Cerebellar ataxia is a neurologic symptom caused by damage or dysfunction in the cerebellum and its pathways that results in loss of coordination, balance and postural control. There is a high rate (93%) of fallings for this population that could limit daily life activities. Pharmacological interventions are not able to modify the balance, therefore, new approaches to rehabilitate must be studied. ctDCS is a non-invasive brain stimulation that seems to be a new and innovator technique to restore ataxia symptoms. The purpose of this study is to evaluate the effects of ctDCS associated with balance training on cerebellar ataxia patients. A counterbalanced crossover, sham-controlled, triple blind trial will be performed. All subjects will receive the real and sham ctDCS associated to balance training. The anodal ctDCS (2 mA, 20 minutes) or sham (2mA, 30 seconds) will be applied during balance training at Biodex Balance System (BBS). The balance will be the primary outcome and will be evaluated through Posture Control at Biodex Balance System. Ataxia' severity and functional mobility will be the secondary outcomes and will be evaluated by the scale for the assessment and rating of ataxia (SARA) and 10 meters walking test, respectively.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

tDCS Associated With Locomotor Training on Functional Mobility of Cerebellar Ataxia

NCT03703830

Ataxia, Cerebellar

ACTIVE_NOT_RECRUITING NA

Effects of Transcranial Direct Current Stimulation Associated With Neurofunctional Rehabilitation in Individuals With Spinocerebellar Ataxias

NCT06974149

Spinocerebellar Ataxia - All Sub-types

NOT_YET_RECRUITING NA

Effects of Deep Brain Stimulation of the Dentate Nucleus on Cerebellar Ataxia

NCT03341416

Cerebellar Ataxia

UNKNOWN NA

tDCS on Motor Rehabiliation of Post Stroke Patients

NCT03446378

Stroke Transcranial Direct Current Stimulation

COMPLETED NA

Manual Dexterity Control After Cerebellar Stimulation

NCT03092570

Stroke

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cerebellar Ataxia Cerebellum; Injury Balance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

ctDCS during Balance training

Group Type EXPERIMENTAL

cerebellar transcranial direct current stimulation

Intervention Type DEVICE

Non-invasive brain stimulation technique is able to modulate the brain activity through a low-intensity current. The anodal will be positioned 1 cm below inion and cathodal in the right deltoid muscle. 20 minutes with a 2mA current.

Balance training

Intervention Type OTHER

Balance training will be performed through the Biodex Balance System for 20 minutes.

ctDCS sham during Balance training

Group Type SHAM_COMPARATOR

Sham cerebellar transcranial direct current stimulation

Intervention Type DEVICE

Non-invasive brain stimulation technique is able to modulate the brain activity through a low-intensity current. The anodal will be positioned 1 cm below inion and cathodal in the right deltoid muscle. 30 seconds with a 2mA current.

Balance training

Intervention Type OTHER

Balance training will be performed through the Biodex Balance System for 20 minutes.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

cerebellar transcranial direct current stimulation

Non-invasive brain stimulation technique is able to modulate the brain activity through a low-intensity current. The anodal will be positioned 1 cm below inion and cathodal in the right deltoid muscle. 20 minutes with a 2mA current.

Intervention Type DEVICE

Sham cerebellar transcranial direct current stimulation

Non-invasive brain stimulation technique is able to modulate the brain activity through a low-intensity current. The anodal will be positioned 1 cm below inion and cathodal in the right deltoid muscle. 30 seconds with a 2mA current.

Intervention Type DEVICE

Balance training

Balance training will be performed through the Biodex Balance System for 20 minutes.

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

ctDCS ctDCS sham

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Cerebellar ataxia
* Score \> 1 ≤ 4 on posture of Scale for assessment and rating of ataxia

Exclusion Criteria

* Individuals with other neurological disorders, postural hypotension, vestibular, visual, cardiovascular or musculoskeletal disorders that affect the performance of the proposed tests;
* Pacemaker;
* History of seizures;
* Metallic implants in the head or neck;
* Medication change (3 months) during the period of study

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No