Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2017-06-12
2019-06-30
Brief Summary
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Detailed Description
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Interestingly, the transcranial direct current stimulation (tDCS) is a non-invasive electro stimulation technique that allows for a modulation of cerebral activity. It has been shown that when applied to the cerebellum, tDCS increases learning performances of healthy subjects. Yet, motor rehabilitation after a CVA highly relies on motor (re)learning. The cerebellar tDCS thus appear as a promising method to enhance the performance of post-CVA motor learning and consequently the benefits of post-CVA rehabilitation.
The current study aims to promote the post CVA neural plasticity by using the tDCS in order to enhance motor learning of the upper limb.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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tDCS Post-CVA
The participants will get a 20min stimulation at a maximal intensity of 2mA
With stimulation
ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
Sham Post-CVA
The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task
No stimulation
ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
tDCS Young Healthy
The participants will get a 20min stimulation at a maximal intensity of 2mA
With stimulation
ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
Sham Young Healthy
The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task
No stimulation
ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
tDCS Older Healthy
The participants will get a 20min stimulation at a maximal intensity of 2mA
With stimulation
ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
Sham Older Healthy
The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task
No stimulation
ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
Interventions
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With stimulation
ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
No stimulation
ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
Eligibility Criteria
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Inclusion Criteria
* Affiliated to the French health insurance or similar organisation
* Signed informed consent
* Clinical examination
For "Post-AVC patients" :
* at least 18 years old
* completed the Moberg Pick-up test with a minimum score of 20 secondes For "Young healthy" group
* 18 = or \> years = or \<30 For "Older healthy" group
* 50 \> or = years = or \< 80
Exclusion Criteria
* Pacemaker, or other electronic implanted devices
* Other central neurological disease
* Pregnancy, breast feeding
* Previous history of neurosurgery or seizures or 1st degree relative with history of seizures
* History of medical neurological or psychiatric disorders
* Participation to another study using cerebral stimulation
* History of bi-polar or recurring depressive disorders
* Planned carotid revascularization, severe caridac disease
* Kidney failure (transaminase \> 2 times normal value)
* Other invalidating condition or deficiency interfering with the study
For "Post-AVC patients" :
* NIHSS score \> 20
* Cerebellar ischemic CVA
18 Years
80 Years
ALL
Yes
Sponsors
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Centre Hospitalier St Anne
OTHER
Responsible Party
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Principal Investigators
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Florence COLLE, MD
Role: PRINCIPAL_INVESTIGATOR
CHSA
Locations
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Centre de Recherche Clinique (CRC) - CHSA
Paris, , France
Service de Médecine Physique et Rédaptation
Paris, , France
Countries
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Central Contacts
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Facility Contacts
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Macarena CUENCA, MD
Role: primary
Cecile Bergot
Role: backup
Florence COLLE, MD
Role: primary
Marie GODARD
Role: backup
Other Identifiers
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D16-P03
Identifier Type: -
Identifier Source: org_study_id