Efficacy Basics of Bihemispheric Motorcortex Stimulation After Stroke

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of the study is to investigate whether the combination of bihemispheric ("dual") transcranial direct current stimulation (tDCS) and motor training on 5 consecutive days facilitates motor recovery in chronic stroke. Results will be compared to a matched group of patients undergoing anodal tDCS as well as a control group receiving sham tDCS. Functional and structural magnetic resonance imaging (MRI) before/after the intervention and during a 3 month follow-up will help investigating neural correlates of expected changes in motor function of the affected upper extremity.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Imaging the Effects of Bihemispheric Transcranial Stimulation and Motor Training After Stroke.

NCT04195412

Stroke

UNKNOWN PHASE2

A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training

NCT02132520

Hemiparesis Stroke

COMPLETED NA

Effects of Dualsite Anodic tDCS on Lower Limbs Function in Patients After Stroke: Randomized, Double-blind, Placebo-controlled, Crossover Trial

NCT04850963

Stroke, Chronic

UNKNOWN NA

tDCS on Motor Rehabiliation of Post Stroke Patients

NCT03446378

Stroke Transcranial Direct Current Stimulation

COMPLETED NA

Neuroregeneration Enhanced by Transcranial Direct Current Stimulation (TDCS) in Stroke

NCT00909714

Stroke

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Stroke Hemiparesis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Dual tDCS + motor training

Motor training of the affected upper extremity combined with dual transcranial direct current stimulation (tDCS).

Group Type EXPERIMENTAL

tDCS

Intervention Type DEVICE

transcranial direct current stimulation (tDCS)

Motor training

Intervention Type BEHAVIORAL

Motor training of the affected upper extremity (5 days, 25 min/day).

Anodal tDCS + motor training

Motor training of the affected upper extremity combined with anodal tDCS.

Group Type ACTIVE_COMPARATOR

tDCS

Intervention Type DEVICE

transcranial direct current stimulation (tDCS)

Motor training

Intervention Type BEHAVIORAL

Motor training of the affected upper extremity (5 days, 25 min/day).

Sham tDCS + motor training

Motor training of the affected upper extremity combined with sham tDCS.

Group Type SHAM_COMPARATOR

tDCS

Intervention Type DEVICE

transcranial direct current stimulation (tDCS)

Motor training

Intervention Type BEHAVIORAL

Motor training of the affected upper extremity (5 days, 25 min/day).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

tDCS

transcranial direct current stimulation (tDCS)

Intervention Type DEVICE

Motor training

Motor training of the affected upper extremity (5 days, 25 min/day).

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* chronic stroke (\>6 months after stroke)
* age: 18 to 80 years
* non-hemorrhagic or hemorrhagic stroke

Exclusion Criteria

* more than 1 stroke
* severe alcohol disease or drug abuse, severe psychiatric disease like depression or psychosis
* severe cognitive deficits
* severe untreated medical conditions
* other neurologic diseases
* severe microangiopathy
* pregnancy

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No