Anterior Corneal Striae in Hypotony

NCT ID: NCT04023123

Last Updated: 2020-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

98 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-17

Study Completion Date

2020-03-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this is to evaluate the biomechanical properties of hypotonous eyes with vertical anterior corneal striae and/or hypotony maculopathy compared to hypotonous eyes without striae.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypotony Ocular Cornea Folds and Rupture of Bowman's Membrane Both Eyes Maculopathy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Anterior Cornea Striae

Eyes with anterior cornea striae present

Ophthalmic imaging

Intervention Type OTHER

Optical coherence tomography Topography Ocular Response Analyzer Optical Biometry Slit lamp photos

Hypotony Maculopathy

Eyes with hypotony maculopathy present

Ophthalmic imaging

Intervention Type OTHER

Optical coherence tomography Topography Ocular Response Analyzer Optical Biometry Slit lamp photos

Hypotony only

Eyes with intraocular pressure less than 10 without cornea striae and/or maculopathy

Ophthalmic imaging

Intervention Type OTHER

Optical coherence tomography Topography Ocular Response Analyzer Optical Biometry Slit lamp photos

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Ophthalmic imaging

Optical coherence tomography Topography Ocular Response Analyzer Optical Biometry Slit lamp photos

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Subjects \>= 18 years of age
* History of glaucoma
* History of glaucoma surgery
* Intraocular pressure of equal to or less than 10 mm Hg by goldmann applanation

Exclusion Criteria

* Coexisting ocular disease that may affect ocular biomechanics, including macular disease, corneal transplant, and uveitis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Duke University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Leon Herndon, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Duke University Health System

Durham, North Carolina, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Pro00102744

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

OCT-A and Amblyopia
NCT05223153 COMPLETED
Astigmatism Post-trabeculectomy
NCT01711190 COMPLETED