HD Mapping of Atrial Fibrillation in Asia Pacific

NCT ID: NCT04022954

Last Updated: 2024-03-29

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-11

Study Completion Date

2021-08-13

Brief Summary

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The aim of this study is to quantify and characterize the outcomes of radiofrequency (RF) ablation after, and the utility of, electroanatomical mapping with the market-released HD mapping catheters Inquiry™ AFocusII™ Double Loop and Advisor™ HD Grid, Sensor Enabled™ with the EnSite Cardiac Mapping System and the EnSite Automap module in subjects with AF in the real-world environment of the Asian population.

Detailed Description

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Conditions

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Paroxysmal Atrial Fibrillation Persistent Atrial Fibrillation

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Inquiry™ AFocusII™ Double Loop

The Inquiry™ AFocus™ catheters are for recording intracardiac signals and cardiac stimulation during diagnostic electrophysiological studies. The Inquiry™ AFocus™ catheters are for use in mapping atrial regions of the heart.

Catheter ablation

Intervention Type DEVICE

Inquiry AFocusII Double Loop and Advisor HD Grid, Sensor Enabled

Advisor™ HD Grid, Sensor Enabled™

The Advisor™ HD Grid Mapping Catheter, Sensor Enabled™, is indicated for multiple electrode electrophysiological mapping of cardiac structures in the heart with recording or stimulation only. This catheter is intended to obtain electrograms in the atrial and ventricular regions of the heart.

Catheter ablation

Intervention Type DEVICE

Inquiry AFocusII Double Loop and Advisor HD Grid, Sensor Enabled

Interventions

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Catheter ablation

Inquiry AFocusII Double Loop and Advisor HD Grid, Sensor Enabled

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject must provide written informed consent for study participation and willing and able to comply with the protocol described evaluations and follow up schedule
2. Subject must be over 18 years of age. (In Japan, the subject must be of 20 years of age or older)
3. Subject is diagnosed with AF as defined by:

* Documented symptomatic paroxysmal AF defined as AF that terminates spontaneously or with intervention within 7 days of onset
* Documented symptomatic persistent AF defined as continuous atrial fibrillation that is sustained beyond 7 days but less than 12 months
4. Subject is indicated for cardiac electroanatomical mapping and RF ablation procedure to treat AF
5. Subject is planned to have electroanatomical mapping performed with the HD mapping catheters under investigation

Exclusion Criteria

1. Previous ablation or surgery in the left atria
2. Implanted left atrial appendage occluder
3. Implanted mitral or tricuspid valve replacement
4. Implanted cardiac defibrillator (ICD)
5. Participation in another clinical investigation that may confound the results of this study
6. Pregnant or nursing
7. Presence of other anatomic or comorbid conditions, or other medical, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements, or impact the scientific soundness of the clinical investigation results.
8. Life expectancy less than 12 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kristin Ruffner, PhD

Role: STUDY_DIRECTOR

EP Program Director

Locations

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Sir Run Run Shaw Hospital

Hangzhou, , China

Site Status

The Second Affiliated Hospital of Xian Jiaotong University

Xi'an, , China

Site Status

Prince of Wales Hospital

Hong Kong, , Hong Kong

Site Status

Kokura Memorial Hospital

Kitakyushu-shi, Fukuoka, Japan

Site Status

University of Tsukuba Hospital

Tsukuba, Ibaraki, Japan

Site Status

Yokosuka Kyosai Hospital

Kanagawa, , Japan

Site Status

Kyoto University Hospital

Kyoto, , Japan

Site Status

Ogaki Municipal Hospital

Ōgaki, , Japan

Site Status

Saga University Hospital

Saga, , Japan

Site Status

Kitasato University Hospital

Sagamihara, , Japan

Site Status

Kyorin University Hospital

Tama, , Japan

Site Status

Korea University Anam Hospital

Seoul, , South Korea

Site Status

Severance Hospital

Seoul, , South Korea

Site Status

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, , Taiwan

Site Status

Taipei Veterans General Hospital (VGH)

Taipei, , Taiwan

Site Status

Countries

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China Hong Kong Japan South Korea Taiwan

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CRD975

Identifier Type: -

Identifier Source: org_study_id

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