Aging, Aged Garlic, Vascular Function and Muscle Oxygenation
NCT ID: NCT04008693
Last Updated: 2020-05-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
28 participants
INTERVENTIONAL
2019-08-26
2020-03-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
DOUBLE
Study Groups
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Kyolic® Hi-Po Formula - Kyolic
Aged garlic extract
Aged Garlic Extract
2.400 mg (four capsules) of a nutritional supplement of aged garlic extract (Kyolic® Hi-Po Formula - Kyolic)
Placebo
Maltodextrin
Placebo
800 mg of maltodextrin (four capsules)
Interventions
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Aged Garlic Extract
2.400 mg (four capsules) of a nutritional supplement of aged garlic extract (Kyolic® Hi-Po Formula - Kyolic)
Placebo
800 mg of maltodextrin (four capsules)
Eligibility Criteria
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Inclusion Criteria
* Cardiovascular diseases
Exclusion Criteria
* HIV positive;
* Alcohol or drug abuse within the past 6 months previous the visit 1;
* Garlic allergy;
60 Years
90 Years
ALL
No
Sponsors
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Universidade Federal do Rio de Janeiro
OTHER
Responsible Party
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Thiago Alvares
Principal Investigator
Principal Investigators
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Thiago Alvares
Role: STUDY_DIRECTOR
Universidade Federal do Rio de Janeiro - Campus Macaé
Thiago Alvares
Role: PRINCIPAL_INVESTIGATOR
Universidade Federal do Rio de Janeiro - Campus Macaé
Locations
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Universidade Federal do Rio de Janeiro - Campus Macaé
Macaé, Rio de Janeiro, Brazil
Countries
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References
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Leitao R, de Oliveira GV, Rezende C, Volino-Souza M, Mesquita J, de Carvalho LL, Alvares TS. Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial. Eur J Nutr. 2022 Oct;61(7):3357-3366. doi: 10.1007/s00394-022-02895-y. Epub 2022 May 4.
Other Identifiers
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86163618.5.0000.5699
Identifier Type: -
Identifier Source: org_study_id
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