Effect of Exercise Training in Alzheimer's Patients

NCT ID: NCT03981159

Last Updated: 2019-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-01

Study Completion Date

2017-11-15

Brief Summary

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The objective of this study was to examine the effects of exercise training on physical function and biochemical markers in elderly Alzheimer's disease patients.

Detailed Description

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Alzheimer's disease is a neurodegenerative disease characterized by progressive and irreversible degeneration of nerve cells. The loss of these cells leads to the continuous decline in muscle function with alterations in biochemical and haematological parameters. The objective of this study was to examine the effects of exercise training on physical function and biochemical markers in elderly Alzheimer's disease patients.

Conditions

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Alzheimer Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Non-pharmacological interventional study
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Active group (under physical training)

Subjects belonging to this arm underwent physical training for three months, twice per week (60 minutes per session).

Group Type EXPERIMENTAL

Physical training

Intervention Type OTHER

Physical training for three months, twice per week (60 minutes per session).

Passive group (no physical training)

Subjects served as controls.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Physical training

Physical training for three months, twice per week (60 minutes per session).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects with official diagnosis of Alzheimer's disease;
* Subjects with MMSE higher than12.

Exclusion Criteria

• Subjects with MMSE below 12 (indicating severe dementia and impairment).
Minimum Eligible Age

80 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Genova

OTHER

Sponsor Role lead

Responsible Party

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Maamer Slimani

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nicola L Bragazzi, MD, PhD, MPH

Role: PRINCIPAL_INVESTIGATOR

Universita degli Studi di Genova

Locations

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University of Genova

Genoa, , Italy

Site Status

Countries

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Italy

Other Identifiers

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ExCiTE-A-17-0020

Identifier Type: -

Identifier Source: org_study_id

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