Longitudinal Follow Up of Eating Disorder Treatment

NCT ID: NCT03946540

Last Updated: 2021-01-05

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 159 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-07-14
• Study Completion Date: 2021-02-28

Brief Summary

The research proposed here seeks to delineate the outcomes of people who have received treatment for an eating disorder at a specialist eating disorder service in childhood or adolescence (hereafter 'former patients'). This will inform our understanding of the maintenance of treatment effects beyond initial trial follow-ups, and together with data collected during treatment will allow for identification of factors predicting chronicity which will inform further treatment development.

Detailed Description

Research Questions

1. Is recovery from an eating disorder in adolescence maintained and associated with good socio-economic outcomes?

2. Is poor outcome from eating disorder treatment in adolescence associated with a chronic course of illness?

3. Are there factors measured during treatment that predict maintenance of outcome or relapse?

This study will use a longitudinal follow up design, contacting former patients of the National and Specialist Child and Adolescent Mental Health Service (CAMHS) Eating Disorder Service, South London and Maudsley National Health Service (NHS) Foundation Trust (CAEDS) between 1/8/2009 and 31/1/2014. These former patients are now aged 16-27. The study will thus provide the longest and largest follow up of treated adolescents to date (n = 358 over a 4-8 year follow up). Former patients will be asked a series of questions by phone/post/email about their health and socio-economic well-being since discharge from the service. This data will be analysed together with assessment and outcome data collected while they were patients of CAEDS.

Measures Data will be collected using a data collection tool developed for this project, as well as the Eating Disorders Examination Questionnaire and the Work and Social Adjustment Scale.

Data collected will comprise:

• Age now
• Employment/education
• Any help sought for eating disorder
• Any help sought for other mental health difficulties
• Current weight
• Current binge/purge symptoms
• Current general well being All data will be self-reported by participants.

Statistical power The primary analysis will be descriptive. We will recruit as many of our original treatment group as possible.

A secondary analysis will be to predict who continues to require mental health care following discharge from CAEDS. Power has been calculated following Babyak's (2004) advice for power calculation for logistic regression of 13 events (continuing mental health care needs) per variable. We have taken figures from the original audit in which 24.1% (n = 69.89) had a poor outcome to hypothesise that a similar proportion of the sample at follow up will have a poor outcome. This is a conservative estimate given the chronicity of eating disorders in adulthood and the longitudinal data of on-going mental health difficulties even in the absence of diagnosable eating disorders. In order to run a logistic regression with 5 predictor variables will require 65 cases with on-going eating disorder symptoms. This will require recruitment of the majority of the original sample assuming the % of on-going difficulties remains the same. Depending on recruitment rate we will adjust analysis accordingly, and reduce the number of predictors in the model.

Data analysis

Planned analyses:

1. Descriptive analysis of key health and socio-economic outcomes for all young people who received treatment in the audited timeframe and split by treatment outcome and diagnosis for between group analysis.

2. Regression analysis to identify predictors of long term outcome from clinical variables measured at baseline assessment and service discharge (including weight, mood, anxiety, eating disorder symptoms)

Conditions

Feeding and Eating Disorders of Childhood; Anorexia Nervosa; Bulimia Nervosa

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: OTHER

Study Groups

L-FED sample

All young people treated in Maudsley Child and Adolescent Eating Disorder Service between 1/8/2009 and 31/1/2014.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• People who were assessed and offered treatment at the National and Specialist CAMHS Eating Disorder Service, South London and Maudsley NHS Foundation Trust between 1/8/2009 and 31/1/2014.

Exclusion Criteria

• young people who were referred for treatment but did not attend assessment
• young people who were referred for treatment but did not meet criteria for an eating disorder
• young people who were referred for treatment but did not accept treatment (or attended for fewer than 3 sessions).

• Minimum Eligible Age: 16 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

South London and Maudsley NHS Foundation Trust

OTHER

Sponsor Role: lead

Responsible Party

Dr Catherine Stewart

Senior Clinical Psychologist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Catherine s Stewart, }hD DClinPsy

Role: PRINCIPAL_INVESTIGATOR

South London and Maudsley NHS Foundation Trust

Locations

Maudsley Centre for Child and Adolescent Eating Disorders

London, , United Kingdom

Countries

United Kingdom

Other Identifiers

L-FED2019

Identifier Type: -

Identifier Source: org_study_id