Trial Measuring the Clinical Impact of the FilmArray® Pneumonia Panel in Critically Ill

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-27

Study Completion Date

2020-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of this study is to measure how the use of Film-Array Pneumonia (FA-PNEU) on respiratory samples of adult patients suspected of acute care pneumonia in the intensive care unit of Saint-Luc University Hospital can accelerate / improve the initiation of the optimal antibiotic treatment.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

FilmArray and Management of ICU Patients With Pneumonia in the Covid-19 Context

NCT04453540

Infectious Disease Pneumonia Molecular Diagnosis +2 more

UNKNOWN

Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia.

NCT04153682

Hospital-acquired Pneumonia

COMPLETED NA

RAPid SOlution for Diagnosis of Respiratory Infection in Pediatric Intensive Care Unit

NCT04773704

Severe Infections Pneumonia With Invasive Ventilation in PICU

COMPLETED

Clinical Impact of a Multiplex Rapid Diagnostic Pneumonia Panel Testing in Critically-ill Patients with Severe Hospital-acquired Pneumonia, Ventilator-associated Pneumonia and Community-acquired Pneumonia with High Risk of Multidrug Resistant Pathogen

NCT06782607

Infectious Disease of Lung Molecular Diagnosis Pneumonia

NOT_YET_RECRUITING NA

FilmArray Pneumonia Panel for Antimicrobial Treatment of HAP/VAP in Intensive Care Units

NCT05214716

Pneumonia, Ventilator-Associated Pneumonia, Hospital Acquired Critically Ill

TERMINATED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The main objective of this trial is to confirm/attest/prove the following statement:

The use of the FilmArray Pneumonia panel on respiratory samples of critically ill suspected with pneumonia, enables a faster microbiological pneumonia diagnosis and an improved therapeutic management of the patient.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pneumonia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Open Randomized study, consecutive 2 weeks-period for observation group and study group

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

control

Respiratory samples are treated according to routine laboratory testing : culture, immuno assays

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention

Respiratory samples are treated according to routine laboratory testing : culture, immuno assays AND molecular testing (FilmArray PNEU) of the endotracheal aspirate sample 24 hours a day.

Group Type EXPERIMENTAL

FilmArray Pneumonia

Intervention Type DIAGNOSTIC_TEST

FilmArray Pneumonia testing of tracheal sample

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

FilmArray Pneumonia

FilmArray Pneumonia testing of tracheal sample

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult patients 18 years, remaining at the intensive care of the Saint-Luc University Hospital
* Recently transferred from emergency care with Community acquired Pneumonia of grade 4 suspicion
* With a Ventilation acquired Pneumonia suspicion

Suspicion will be based on symptoms, clinical, biological and radiological criteria.

Exclusion Criteria

* Patients from whom no respiratory sample can be obtained
* Patients benefitting from palliative care
* Insufficient volume of the respiratory sample after routine testing to perform the FA-PNEU test.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No