Preclinical Cardiomyopathy and Autonomic Function in Type 1 Diabetes
NCT ID: NCT03930004
Last Updated: 2019-10-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
80 participants
OBSERVATIONAL
2018-07-06
2019-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Type 1 diabetic patients
Patients diagnosed with type 1 diabetes mellitus with criteria for cardiovascular autonomic neuropathy, asymptomatic, normotensive, with negative medical history of cardiovascular disease.
Transthoracic echocardiography, including: tissue Doppler indices of diastolic filling and speckle tracking for systolic and diastolic strain/strain rate, exclusion of valvular abnormalities, assessment of heart structure and function.
No interventions assigned to this group
Control - Healthy subjects
Fifteen age- and sex-matched healthy control subjects, asymptomatic, normotensive, with negative medical history of cardiovascular disease.
Transthoracic echocardiography, including: tissue Doppler indices of diastolic filling and speckle tracking for systolic and diastolic strain/strain rate, exclusion of valvular abnormalities, assessment of heart structure and function.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* coronary artery disease
* heart valve disease
* ventricular dysfunction
* radiotherapy or chemotherapy
* alcoholism
* limited acoustic window
20 Years
55 Years
ALL
Yes
Sponsors
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Roberto Léo da Silva
OTHER
Responsible Party
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Roberto Léo da Silva
Clinical Director
Principal Investigators
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Thais R Weber, MD
Role: STUDY_CHAIR
HU/UFSC
Locations
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HU/UFSC
Florianópolis, Santa Catarina, Brazil
Countries
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Other Identifiers
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HU-UFSC 2018
Identifier Type: -
Identifier Source: org_study_id
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