Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT ID: NCT03925129

Last Updated: 2021-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-11

Study Completion Date

2020-03-13

Brief Summary

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This is a double-blinded, randomized, placebo-controlled trial evaluating the use of High-frequency Transcutaneous Electrical Nerve Stimulation (HfTENS) compared to sham TENS for pain control during medication abortion with mifepristone and misoprostol through 70 days' gestation.

Detailed Description

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Conditions

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Abortion in First Trimester

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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TENS

Group Type EXPERIMENTAL

high frequency TENS treatment

Intervention Type DEVICE

Treatment with high frequency for minimum of 1 hour after misoprostol administration

Sham TENS

Group Type SHAM_COMPARATOR

Sham TENS treatment

Intervention Type DEVICE

Treatment with sham TENS device for minimum of 1 hour after misoprostol administration

Interventions

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high frequency TENS treatment

Treatment with high frequency for minimum of 1 hour after misoprostol administration

Intervention Type DEVICE

Sham TENS treatment

Treatment with sham TENS device for minimum of 1 hour after misoprostol administration

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients seeking medication abortion with a definite, singleton, intrauterine pregnancy (IUP) \< 70 days' gestation on ultrasound
* Rapid Estimate of Adult Literacy in Medicine-Short Form (REALM-SF)22 score \> 4
* Age equal to or greater than 18 years
* Provide informed consent to participate
* Willing to adhere to study procedures, including access to a smart phone, ability to receive text messages and answer online surveys on smart phone

Exclusion Criteria

* Contraindication to medication abortion
* Allergy to mifepristone or misoprostol
* Contraindication or allergy to ibuprofen
* History of cardiac arrhythmia
* Presence of an implantable device with electrical discharge, i.e. cardiac pacemaker
* History of chronic pain disorder
* Any opioid use during previous 30 days
* Current or prior use of TENS
* BMI \> 30
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Planned Parenthood of Greater New York

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ariella Goldman, MD

Role: PRINCIPAL_INVESTIGATOR

Planned Parenthood of Greater New York

Locations

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Planned Parenthood of New York City - Margaret Sanger Center

New York, New York, United States

Site Status

Countries

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United States

References

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Goldman AR, Porsch L, Hintermeister A, Dragoman M. Transcutaneous Electrical Nerve Stimulation to Reduce Pain With Medication Abortion: A Randomized Controlled Trial. Obstet Gynecol. 2021 Jan 1;137(1):100-107. doi: 10.1097/AOG.0000000000004208.

Reference Type DERIVED
PMID: 33278292 (View on PubMed)

Other Identifiers

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TENS MAB

Identifier Type: -

Identifier Source: org_study_id

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