Oncologic Risk of Rectal Preservation Against Medical Advice After Chemoradiotherapy for Rectal Cancer
NCT ID: NCT03923309
Last Updated: 2019-04-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
142 participants
OBSERVATIONAL
2016-05-01
2017-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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Intended rectal preservation
When rectal preservation (non-operative management or local excision) was agreed by their surgeon.
No interventions assigned to this group
Unintended rectal preservation
When rectal preservation (non-operative management or local excision) was disagreed by their surgeon.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* neoadjuvant radiotherapy or chemoradiotherapy
* no radical surgery after neoadjuvant therapy
Exclusion Criteria
* other fatel disease
* incompletion of half of radiotherapy course
* metastasis on initial presentation
18 Years
ALL
No
Sponsors
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National Cancer Center, Korea
OTHER_GOV
Seoul National University Bundang Hospital
OTHER
Seoul National University Hospital
OTHER
Responsible Party
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Sung-Bum Kang
Colorectal Surgeon, University Professor
Principal Investigators
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Jae-Hwan Oh, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
National Cancer Center, Korea
Kyu Joo Park, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
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National Cancer Center, Korea
Goyang-si, Gyeonggi-do, South Korea
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Seoul National University Hospital
Seoul, , South Korea
Countries
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References
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Ellis CT, Samuel CA, Stitzenberg KB. National Trends in Nonoperative Management of Rectal Adenocarcinoma. J Clin Oncol. 2016 May 10;34(14):1644-51. doi: 10.1200/JCO.2015.64.2066. Epub 2016 Mar 28.
Cassidy RJ, Switchenko JM, Cheng E, Jiang R, Jhaveri J, Patel KR, Tanenbaum DG, Russell MC, Steuer CE, Gillespie TW, McDonald MW, Landry JC. Health care disparities among octogenarians and nonagenarians with stage II and III rectal cancer. Cancer. 2017 Nov 15;123(22):4325-4336. doi: 10.1002/cncr.30896. Epub 2017 Jul 31.
Lee DY, Teng A, Pedersen RC, Tavangari FR, Attaluri V, McLemore EC, Stern SL, Bilchik AJ, Goldfarb MR. Racial and Socioeconomic Treatment Disparities in Adolescents and Young Adults with Stage II-III Rectal Cancer. Ann Surg Oncol. 2017 Feb;24(2):311-318. doi: 10.1245/s10434-016-5626-0. Epub 2016 Oct 20.
Other Identifiers
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B-1711/433-102
Identifier Type: -
Identifier Source: org_study_id
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