TEAS Reduces Remifentanil Consumption

NCT ID: NCT03912688

Last Updated: 2019-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

153 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-31

Study Completion Date

2015-12-31

Brief Summary

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Transcutaneous electrical acupoint stimulation (TEAS) has been shown to decrease the need of opioids including remifentanil during anaesthesia. However, it is not clear whether combination of two or more acupoints could induce stronger analgesia. Moreover, evidence for the long-term effect of TEAS has been limited. The present study was to compare the short-term and long-term effect on pain of dual-acupoint and single-acupoint TEAS.

Detailed Description

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Conditions

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Anesthesia Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors
Interventions were performed by a designated investigator who was not involved in the anaesthesia or the follow-up. The stimulator was placed in an opaque box to blind the surgical team and the anesthesiologists to the group allocation.

Study Groups

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single acupoint stimulation

Group Type EXPERIMENTAL

acupoint stimulation

Intervention Type DEVICE

single acupoint

Intervention Type DEVICE

dual acupoints stimulation

Group Type EXPERIMENTAL

acupoint stimulation

Intervention Type DEVICE

dual acupoints

Intervention Type DEVICE

no stimulation

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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acupoint stimulation

Intervention Type DEVICE

single acupoint

Intervention Type DEVICE

dual acupoints

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18 to 65 yrs
* body mass index (BMI) of 18 to 30 kg/m2
* elective radical mastectomy under general anaesthesia

Exclusion Criteria

* contradictions to TEAS
* difficulties in communication
* histories of general anaesthesia
* drug or alcohol abuse or addiction
* cardiac dysfunction or severe hypertension
* confirmed hepatic dysfunction and renal impairment
* the participants recruited into other clinical trials during last three months
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Air Force Military Medical University, China

OTHER

Sponsor Role lead

Responsible Party

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Zhihong LU

principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Kuhn LA. Editorial: Acupuncture anesthesia for open heart surgery. Am J Cardiol. 1974 Aug;34(2):254-5. doi: 10.1016/0002-9149(74)90207-0. No abstract available.

Reference Type BACKGROUND
PMID: 4843161 (View on PubMed)

Lu Z, Dong H, Wang Q, Xiong L. Perioperative acupuncture modulation: more than anaesthesia. Br J Anaesth. 2015 Aug;115(2):183-93. doi: 10.1093/bja/aev227.

Reference Type RESULT
PMID: 26170347 (View on PubMed)

Wang H, Xie Y, Zhang Q, Xu N, Zhong H, Dong H, Liu L, Jiang T, Wang Q, Xiong L. Transcutaneous electric acupoint stimulation reduces intra-operative remifentanil consumption and alleviates postoperative side-effects in patients undergoing sinusotomy: a prospective, randomized, placebo-controlled trial. Br J Anaesth. 2014 Jun;112(6):1075-82. doi: 10.1093/bja/aeu001. Epub 2014 Feb 26.

Reference Type RESULT
PMID: 24576720 (View on PubMed)

Yan B, Li K, Xu J, Wang W, Li K, Liu H, Shan B, Tang X. Acupoint-specific fMRI patterns in human brain. Neurosci Lett. 2005 Aug 5;383(3):236-40. doi: 10.1016/j.neulet.2005.04.021.

Reference Type RESULT
PMID: 15876491 (View on PubMed)

Other Identifiers

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XJA-S-20190212

Identifier Type: -

Identifier Source: org_study_id

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