Neurohumoral Mechanism of Deferent Frequency Transcutaneous Electrical Acupoint Stimulation(TEAS)

NCT ID: NCT02611388

Last Updated: 2015-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-31

Study Completion Date

2016-06-30

Brief Summary

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The purpose of this study is to explore the neurohumoral mechanism of deferent frequency TEAS pretreatment.

Detailed Description

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Patients were randomly assigned to three groups, receiving TEAS 30min before anesthesia. The frequency of high frequency group is set to 10/50HZ, low frequency group is 2/10HZ, and the fake stimulation group only attach electrodes without electric current. Acupoint selection is bilateral Neiguan points(PC6). Venous blood is collected 4ml before and immediately after TEAS respectively. Heart rate variability is monitored continuously during the 30min TEAS. The adverse events recorded.

Conditions

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Hypotension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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2/10HZ TEAS pretreatment

Patients were given 30min of 2/10HZ TEAS before anesthesia

Group Type EXPERIMENTAL

TEAS (transcutaneous electrical acupoint stimulation)

Intervention Type DEVICE

2/10HZ Electric stimulation was given through electrode attached to specific acupoints

10/50HZ TEAS pretreatment

Patients were given 30min of 10/50HZ TEAS before anesthesia

Group Type EXPERIMENTAL

TEAS (transcutaneous electrical acupoint stimulation)

Intervention Type DEVICE

10/50HZ Electric stimulation was given through electrode attached to specific acupoints

fake stimulation

Patients were only attached electrodes without electric current

Group Type SHAM_COMPARATOR

fake stimulation

Intervention Type DEVICE

Patients were only attached electrodes without electric current

Interventions

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TEAS (transcutaneous electrical acupoint stimulation)

2/10HZ Electric stimulation was given through electrode attached to specific acupoints

Intervention Type DEVICE

TEAS (transcutaneous electrical acupoint stimulation)

10/50HZ Electric stimulation was given through electrode attached to specific acupoints

Intervention Type DEVICE

fake stimulation

Patients were only attached electrodes without electric current

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 18yrs-65yrs
* ASA 1-2
* Scheduled for elective operation under general anesthesia
* BMI 18-30kg/m2
* Informed consented

Exclusion Criteria

* Contraindications to TEAS
* Communication difficulty with researchers
* Addicted to alcohol, analgesics or other drugs
* Cardiac insufficiency or high blood pressure without controlled
* Hepatic or renal dysfunction
* Participate in the other clinical trial 3 month before the enrollment
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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wangqiang

OTHER

Sponsor Role lead

Responsible Party

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wangqiang

Doctor

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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Qiang Wang

Role: CONTACT

86-29-84775343

References

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Lu Z, Dong H, Wang Q, Xiong L. Perioperative acupuncture modulation: more than anaesthesia. Br J Anaesth. 2015 Aug;115(2):183-93. doi: 10.1093/bja/aev227.

Reference Type BACKGROUND
PMID: 26170347 (View on PubMed)

Other Identifiers

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XJH-A-2015-10-28

Identifier Type: -

Identifier Source: org_study_id