Effect of Transcutaneous Electrical Acupoint Stimulation on Dyspareunia

NCT ID: NCT06730776

Last Updated: 2024-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-15

Study Completion Date

2025-05-30

Brief Summary

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Transcutaneous electrical acupoint stimulation (TEAS)was proven to stimulate the secretion of endogenous opioid peptides which are partial substitutes for the exogenous opioids stimulated by drugs in the central nervous system and can thus relieve pain. Till now there is no previous study that investigates the effect of TEAS on dyspareunia. This study will determine the effect of transcutaneous acupoint stimulation on dyspareunia.

Patients will be divided randomly into two groups equal in number: The control group will receive only topical medication. The study group will receive Acu-TENS and topical medication.

Detailed Description

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Patients will be divided randomly into two groups equal in number:

Control group (Group A): It will include 19 women with dyspareunia. They will receive only topical medication (lidocaine ointment applied as required for symptoms and 30 minutes before sexual activity).

Study group (GroupB): It will include 19 women with dyspareunia. They will receive Acu-TENS (30 minutes per session, once per week for 10 weeks), and topical medication (lidocaine ointment applied as required for symptoms and 30 minutes before sexual activity). All females will be given a full explanation of the study protocol and a consent form will be signed by each female before participating in the study

Conditions

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Dyspareunia (Female)

Keywords

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dyspareunia,

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Control group (group A)

It will include 19 women with dyspareunia. They will receive only topical medication (lidocaine ointment applied as required for symptoms and 30 minutes before sexual activity)

Group Type ACTIVE_COMPARATOR

Topical medication

Intervention Type OTHER

It will be given to all participants in both groups (A\&B). The most commonly prescribed topical medication is lidocaine ointment 5% (Xylocaine jelly 2% or ointment 5%; AstraZeneca Pharmaceuticals LP, Wilmington, DE), applied as required for symptoms and for 30 minutes before sexual activity.

Study group (group B)

It will include 19 women with dyspareunia. They will receive Acu-TENS (30 minutes per session, once per week for 10 weeks), topical medication(lidocaine ointment applied as required for symptoms and 30 minutes before sexual activity)

Group Type EXPERIMENTAL

Topical medication

Intervention Type OTHER

It will be given to all participants in both groups (A\&B). The most commonly prescribed topical medication is lidocaine ointment 5% (Xylocaine jelly 2% or ointment 5%; AstraZeneca Pharmaceuticals LP, Wilmington, DE), applied as required for symptoms and for 30 minutes before sexual activity.

Transcutaneous electrical acupoint stimulation

Intervention Type OTHER

This procedure will be applied for group B only. Before starting the first treatment session, each patient will be instructed briefly about the nature of the treatment to gain the patient's confidence and cooperation. This procedure will be performed by using TENS device on acupoints as the following: The participating woman will be placed in a relaxed comfortable supine position with her back well supported. The surface of the treated skin and the electrodes will be cleaned with alcohol wipe. The TENS protocol consists of a 30-minute weekly. session for 10 weeks of biphasic pulses with modulation 0/10-50 Hz of frequency and 300/100/3000 microseconds of pulse duration (s). The intensity parameter will be adapted individually according to each woman's perception, and modulated so that it is applied without discomfort, ranging between 10 and 100 mA (pulsing sensation) (Dionisi and Senatori ,2011)

Interventions

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Topical medication

It will be given to all participants in both groups (A\&B). The most commonly prescribed topical medication is lidocaine ointment 5% (Xylocaine jelly 2% or ointment 5%; AstraZeneca Pharmaceuticals LP, Wilmington, DE), applied as required for symptoms and for 30 minutes before sexual activity.

Intervention Type OTHER

Transcutaneous electrical acupoint stimulation

This procedure will be applied for group B only. Before starting the first treatment session, each patient will be instructed briefly about the nature of the treatment to gain the patient's confidence and cooperation. This procedure will be performed by using TENS device on acupoints as the following: The participating woman will be placed in a relaxed comfortable supine position with her back well supported. The surface of the treated skin and the electrodes will be cleaned with alcohol wipe. The TENS protocol consists of a 30-minute weekly. session for 10 weeks of biphasic pulses with modulation 0/10-50 Hz of frequency and 300/100/3000 microseconds of pulse duration (s). The intensity parameter will be adapted individually according to each woman's perception, and modulated so that it is applied without discomfort, ranging between 10 and 100 mA (pulsing sensation) (Dionisi and Senatori ,2011)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women complain of secondary dyspareunia, diagnosed and referred by the gynecologist.
* Multiparous women.
* Their ages will range from 25-35 years.
* Their body BMI will be less than 35 kg/m².
* Their pain level on the VAS will be ≥ 4.
* All the women were negative for vaginal infections caused by viruses, bacteria or fungi.

Exclusion Criteria

* Pregnancy
* Malignancy.
* The presence of an intrauterine device, vaginal infection, or skin/mucous lesions.
* Diabetes mellitus.
* Dermatological abnormalities on the skin at acupuncture point.
* Severe uncontrolled cardiac patients or implanted cardiac rhythm devices.
* Dyspareunia with endometriosis.
* Fearing from electricity.
Minimum Eligible Age

25 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Marwa gamal abdelrahman ahmed

Master student at Faculty of Physical Therapy, Cairo University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Doaa A Osman

Role: STUDY_CHAIR

Department of Women's Health, Faculty of Physical Therapy, Cairo University

Locations

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Faculty of Physical Therapy

Giza, Egypt, Egypt

Site Status

Countries

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Egypt

Central Contacts

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Marwa GA Ahmed

Role: CONTACT

Phone: 01018637863

Email: [email protected]

Manal A El-Shafei

Role: CONTACT

Phone: 01220664518

Email: [email protected]

Facility Contacts

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Marwa GA Ahmed

Role: primary

Other Identifiers

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P.T.REC/012/005373

Identifier Type: -

Identifier Source: org_study_id