The Pathogenesis of Human Senile Cataract

NCT ID: NCT03907358

Last Updated: 2019-04-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-12-07

Study Completion Date

2020-06-30

Brief Summary

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To study the pathological mechanism of cataract by genomics, transcriptomics, and proteomics.

Detailed Description

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Tissue samples and aqueous humor samples will be collected from each individual patients by cataract surgery. After sample treatment, different techniques will be applied for analysis. And bioinformatics approach is applied for data treatment and analysis.The data of genomics, transcriptomics, and proteomics will be analyzed for study of pathological mechanism of cataract.

Conditions

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Cataract

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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cataract in old age

phacoemulsification

Intervention Type PROCEDURE

cataract in young age

phacoemulsification

Intervention Type PROCEDURE

Interventions

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phacoemulsification

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with the explicit diagnosis of cataract (including senile cataract, congenital cataract, complicated cataract, metabolic cataract, traumatic cataract, etc.) in the operated eye are willing to undergo cataract surgery.

Exclusion Criteria

* Patients whose cataracts need not be operated
* Patients with any contraindications to cataract surgery
* Patients are unwilling to undergo cataract surgery
Minimum Eligible Age

5 Years

Maximum Eligible Age

94 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Haidong Zou

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University

Shanghai, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Haidong Zou

Role: CONTACT

86-21-63240090 ext. 6833

Bijun Zhu

Role: CONTACT

Facility Contacts

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Haidong Zou, Dr.

Role: primary

86-21-63240090 ext. 6833

Other Identifiers

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Shanghai1st-cataract-001

Identifier Type: -

Identifier Source: org_study_id

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