Correlation Analysis of Lens Nucleus Density and Surgical Parameters Based on Ss-oct and Scheimpflug Technology

NCT ID: NCT05028530

Last Updated: 2021-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

53 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-01

Study Completion Date

2021-12-30

Brief Summary

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To study the correlation between three different lens nuclear opacity classification methods and intraoperative phacoemulsification parameters .

Detailed Description

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Slit-lamp lens images, Pentacam and IOL-Master 700 images were collected in patients with dilated pupil before cataract surgery, and phacoemulsification parameters on the Centurion phacoemulsification machine (Alcon) screen were recorded. Spearman correlation analysis was used to analyze the correlation between lens nuclear density and phacoemulsification parameters based on SS-OCT and Scheimpflug techniques.

Conditions

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Age-related Cataract

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

1. Age-related cataracts performed by the same surgeon in our hospital;
2. Pupil diameter can be enlarged more than 6 millimetre.

Exclusion Criteria

1. The pupil diameter cannot be dilated greater than 6mm;
2. previously ocular surgery or laser treatment;
3. history of ocular trauma;
4. other ocular diseases such as keratoconus, glaucoma and retinal detachment;
5. corneal opacities caused by leucoma, pterygium and other diseases;
6. lens dislocation or complicated cataract surgery (any complications during/after the operations);
7. poor fixation leading to low image quality or inability to cooperate with examinations.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wenzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Yune Zhao

Vice president of Eye Hospital of Wenzhou Medical University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yune Zhao

Role: STUDY_DIRECTOR

Ophthalmology and Optometry Hospital

Locations

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Ophthalmology and Optometry Hospital

Wenzhou, Zhejiang, China

Site Status

Countries

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China

Central Contacts

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Yune Zhao

Role: CONTACT

8613819707056

Lulu Chen

Role: CONTACT

19883736563

Facility Contacts

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zhao yun-e

Role: primary

+86 13819707056

References

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Wang W, Zhang J, Gu X, Ruan X, Chen X, Tan X, Jin G, Wang L, He M, Congdon N, Liu Z, Luo L, Liu Y. Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography. Br J Ophthalmol. 2022 Jun;106(6):790-794. doi: 10.1136/bjophthalmol-2020-318334. Epub 2021 Jan 13.

Reference Type BACKGROUND
PMID: 33441322 (View on PubMed)

Makhotkina NY, Berendschot TTJM, van den Biggelaar FJHM, Weik ARH, Nuijts RMMA. Comparability of subjective and objective measurements of nuclear density in cataract patients. Acta Ophthalmol. 2018 Jun;96(4):356-363. doi: 10.1111/aos.13694. Epub 2018 Mar 25.

Reference Type BACKGROUND
PMID: 29575599 (View on PubMed)

Lim SA, Shin JY, Chung SH. Useful Prediction of Phacodynamics by Scheimpflug Lens Densitometry in Patients over Age 70. Semin Ophthalmol. 2017;32(4):482-487. doi: 10.3109/08820538.2015.1120756. Epub 2016 Apr 19.

Reference Type BACKGROUND
PMID: 27092580 (View on PubMed)

Gupta M, Ram J, Jain A, Sukhija J, Chaudhary M. Correlation of nuclear density using the Lens Opacity Classification System III versus Scheimpflug imaging with phacoemulsification parameters. J Cataract Refract Surg. 2013 Dec;39(12):1818-23. doi: 10.1016/j.jcrs.2013.05.052.

Reference Type BACKGROUND
PMID: 24286839 (View on PubMed)

Chen D, Li Z, Huang J, Yu L, Liu S, Zhao YE. Lens nuclear opacity quantitation with long-range swept-source optical coherence tomography: correlation to LOCS III and a Scheimpflug imaging-based grading system. Br J Ophthalmol. 2019 Aug;103(8):1048-1053. doi: 10.1136/bjophthalmol-2018-312661. Epub 2018 Oct 12.

Reference Type BACKGROUND
PMID: 30315132 (View on PubMed)

Panthier C, de Wazieres A, Rouger H, Moran S, Saad A, Gatinel D. Average lens density quantification with swept-source optical coherence tomography: optimized, automated cataract grading technique. J Cataract Refract Surg. 2019 Dec;45(12):1746-1752. doi: 10.1016/j.jcrs.2019.07.033.

Reference Type BACKGROUND
PMID: 31856985 (View on PubMed)

Panthier C, Burgos J, Rouger H, Saad A, Gatinel D. New objective lens density quantification method using swept-source optical coherence tomography technology: Comparison with existing methods. J Cataract Refract Surg. 2017 Dec;43(12):1575-1581. doi: 10.1016/j.jcrs.2017.09.028.

Reference Type BACKGROUND
PMID: 29335103 (View on PubMed)

Other Identifiers

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LZL nucleus density

Identifier Type: -

Identifier Source: org_study_id

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