Enthesitis in Patients With Knee Osteoarthritis

NCT ID: NCT03897829

Last Updated: 2019-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-29

Study Completion Date

2019-05-30

Brief Summary

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The current study was conducted to estimate the prevalence of knee cap enthesitis in patients with knee osteoarthritis and its relation to knee function.

Detailed Description

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The current study will based on a cross sectional hospital-based survey, conducted among patients with knee osteoarthritis , Knee will assessed for the following items in both sides while Patient lying supine with the knee flexed 40 degrees:

1. Superior pole of the patella - quadriceps tendon enthesis: ● Quadriceps tendon thickness \>6.1 mm ● Suprapatellar bursitis ● Superior pole of patella erosion ● Superior pole of patella enthesophyte.
2. Inferior pole of the patella - proximal patellar ligament enthesis: ● Patellar ligament thickness \>4 mm ● Inferior pole of patella erosion ● Inferior pole of patella enthesophyte.
3. Tibial tuberosity - distal patellar ligament enthesis ● Patellar ligament thickness \>4 mm ● Infrapatellar bursitis ● Tibial tuberosity erosion ● Tibial tuberosity enthesophyte.

Knee functional status was assessed using Knee injury and Osteoarthritis Outcome Score (KOOS) scale for Pain, other Symptoms, Activities of Daily Living (ADL), Sport and Recreation Function (Sport/Rec) and knee-related Quality of Life (QOL). Low knee function was considered if the patient had score 50 or more in any KOOS scale parameter.

Conditions

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Osteoarthritis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Primary Knee OA diagnosed according to: American College of Rheumatology Radiologic Criteria for Knee Osteoarthritis.
* Kellegren - Lawrance scale grade II.
* On regular treatment by analgesics, or NSAIDS either topical or systemic.

Exclusion Criteria

* Recent Knee trauma or intra-articular procedures.
* Previous knee surgery.
* Inflammatory joint diseases, as rheumatoid arthritis, crystal arthritis, and spondyloarthropathy
* chronic systemic diseases that could affect patient functional ability; e.g renal, liver, cardiac impairment, or neurological disorder.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abogamal

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar Faculty of medicine, Rheumatology Department

Cairo, , Egypt

Site Status

Al-Azhar university hospitals

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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aswu/320/1/19

Identifier Type: -

Identifier Source: org_study_id

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