Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

NCT ID: NCT03845283

Last Updated: 2024-05-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

198 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-02

Study Completion Date

2024-09-01

Brief Summary

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Cardiovascular disease (CVD) is the leading cause of death in the United States. Cardiac rehabilitation (CR) is the main treatment for heart attacks and other types of CVD. It is based on science, it saves money, and it is widely-available. Each session (of which there are a few each week for 3 months) combines supervised exercise and instruction. The goals are to improve overall health and reduce cardiovascular risk in individuals with established CVD. CR produces almost no weight loss (WL); if a person has excess weight while in CR (the majority of participants have overweight or obesity), losing weight could really reduce their risk of having another heart attack. The best treatment available for weight loss, in-person behavioral weight loss interventions (BWLs), produce enough WL that they improve health and disease risk/severity. However, in-person BWLs are too much work to be carried out in CR. A previous fully automated 3-month online program, Rx Weight Loss (RxWL), produced good WL in many different settings. Dr. Goldstein aims to tailor RxWL for use in CR. The study will use the Multiphase Optimization Strategy (MOST) to test innovative eHealth/mHealth intervention components that might work well for people when combined with RxWL. The study will include 160 patients (each randomized to receive 0-4 of the components). The components are: (a) a Fitbit with a goal-setting program; (b) a bite counting device; (c) a Web-based virtual reality (VR) intervention ; and (d) virtual meetings. By the 6-month follow-up, the investigators will know if any of those 4 components helped people lose more weight. If a component produced at least 2% WL, it will be studied further by being included in a new intervention to be tested in the next study.

Detailed Description

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Conditions

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Cardiovascular Diseases Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Physical Activity

Participants will receive the core 6-month weight loss program and the tailored intervention to promote structured physical activity.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Core Program

Participants will receive the core 6-month weight loss program alone. This program includes weekly lessons for the first 12 weeks and monthly lessons for the remaining 12 weeks. Participants will track their intake, physical activity, and weight, input these data into the system, and received tailored feedback.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity & Virtual Meetings

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Virtual Meetings

Participants will receive the core 6-month weight loss program and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Physical Activity & Virtual Reality

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, and access to the virtual reality platform for behavioral weight loss skills training.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Virtual Reality

Participants will receive the core 6-month weight loss program and access to the virtual reality platform for behavioral weight loss skills training.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Physical Activity, Virtual Reality, & Virtual Meetings

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, the virtual meetings to support weight loss, and access to the virtual reality platform for behavioral weight loss skills training.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Virtual Reality & Virtual Meetings

Participants will receive the core 6-month weight loss program, access to the virtual reality platform for behavioral weight loss skills training, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Physical Activity & Bite Counter

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, and the Bite Counter device to reduce dietary intake.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Bite Counter

Participants will receive the core 6-month weight loss program and the Bite Counter device to reduce dietary intake.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Physical Activity, Bite Counter, & Virtual Meetings

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, the Bite Counter device to reduce dietary intake, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Bite Counter & Virtual Meetings

Participants will receive the core 6-month weight loss program, the Bite Counter device to reduce dietary intake, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Physical Activity, Bite Counter, & Virtual Reality

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, the Bite Counter device to reduce dietary intake, and access to the virtual reality platform for behavioral weight loss skills training.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Bite Counter & Virtual Reality

Participants will receive the core 6-month weight loss program, the Bite Counter device to reduce dietary intake, and access to the virtual reality platform for behavioral weight loss skills training.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Physical Activity, Bite Counter, Virtual Reality & Meetings

Participants will receive the core 6-month weight loss program, the tailored intervention to promote structured physical activity, the Bite Counter device to reduce dietary intake, access to the virtual reality platform for behavioral weight loss skills training, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Physical Activity Intervention

Intervention Type BEHAVIORAL

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Bite Counter, Virtual Reality, & Virtual Meetings

Participants will receive the core 6-month weight loss program, the Bite Counter device to reduce dietary intake, access to the virtual reality platform for behavioral weight loss skills training, and the virtual meetings to support weight loss.

Group Type EXPERIMENTAL

Online Behavioral Weight Loss Program

Intervention Type BEHAVIORAL

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Bite Counter

Intervention Type BEHAVIORAL

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Virtual Reality

Intervention Type BEHAVIORAL

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Virtual Meetings

Intervention Type BEHAVIORAL

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Interventions

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Online Behavioral Weight Loss Program

A self-guided, online program that helps participants reduce excess calories and gradually increase physical activity.

Intervention Type BEHAVIORAL

Physical Activity Intervention

An program designed to help participants gradually increase their physical activity and maintain an active lifestyle. The program encourages bouts of moderate-to-vigorous physical activity. Participants in this group will receive a Fitbit Versa to help them monitor their physical activity that they will be advised to wear daily. Participants will receive brief (5-10 minute) lessons weekly for the first 3 months and monthly for the last 3 months.

Intervention Type BEHAVIORAL

Bite Counter

Participants will receive a Bite Counter device to help them monitor and reduce their within-meal consumption. Participants will be asked to wear the device daily.

Intervention Type BEHAVIORAL

Virtual Reality

This program allows participants to practice behavioral weight loss skills using a virtual reality system compatible with their home device. This program helps patients practice these skills in the following artificial settings: at home, at work, at the gym, and at a party. Each participant will be asked to play through each scene at least once during their participation, though they are encouraged to use the program regularly.

Intervention Type BEHAVIORAL

Virtual Meetings

Participants will attend virtual meetings using their own device. Each virtual meeting focuses on a specific topic that will help patients lose weight. Participants are asked to virtually attend at least 6 meetings during their participation. There is no limit to how many they can attend. The meeting topics will rotate and repeat on a schedule.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* currently a participant in The Miriam Hospital's or Newport Hospital's outpatient phase II cardiac rehabilitation program
* medical clearance to participate by the Medical Director
* a body mass index (BMI) between 27-45 kg/m2
* must have a personal computer in their home with internet access
* must read and understand English
* willing to use technology to assist with weight loss

Exclusion Criteria

* currently in another weight loss program
* taking weight loss medication
* weight loss of ≥ 5% of body weight in the past 6 months
* currently pregnant, lactating, \< 6 months post-partum, or plans to become pregnant during the next year
* report of loss of consciousness on the Physical Activity Readiness Questionnaire
* New York Heart Association Class IV heart failure
* heart transplant in the last 3 months
* receipt of left ventricular assist device in the last 2 months
* a physician diagnosis of dementia
* a physician prescription for 24 hours of oxygen therapy daily
* coronary artery bypass surgery in the last 4 weeks
* current participation in dialysis
* inability to walk 1 block without stopping
* report of conditions that in the opinion of the investigators would render them potentially unlikely to follow the protocol including terminal illness, substance abuse, eating disorder, or other significant psychiatric problems
Minimum Eligible Age

21 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role collaborator

The Miriam Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Weight Control and Diabetes Research Center

Providence, Rhode Island, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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K23HL136845

Identifier Type: NIH

Identifier Source: secondary_id

View Link

K23HL136845

Identifier Type: NIH

Identifier Source: org_study_id

View Link

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